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  Scientists at deCODE genetics have reported the discovery of seven novel and common single-letter variations in the sequence of the human genome (SNPs) that are involved in modulating the electrical impulses that govern the working of the heart.Two of these SNPs, which correlate with electrocardiogram (ECG or EKG) measurements that are used in the clinical evaluation of heart health and activity, were then shown to confer increased risk of atrial fibrillation (AF), one of the most common causes of irregular heartbeat and a leading cause of stroke.The paper, 鈥淪everal common variants modulate heart rate, PR interval and QRS duration,鈥?is published online in Nature Genetics, and will appear in an upcoming prin dunk low t addition of the journal.The deCODE team began by correlating ECG measurements with yeezy sneaker  genome-wide SNP data from more than 40,000 Icelandic participants in its gene discovery program. This search identified one novel SNP infl yeezy foam uencing heart rate and four each linked to PR interval and QR  LAHORE:The former chairperson of Government College University鈥檚 (GCU) zoology department has donated Rs1 million to the university for the  adidas campus gr眉n scholarships of financially-challenged orphan students.Prof Dr Nusrat Jahan handed over the cheque for GCU鈥檚 Endowment Fund Trust (GCU-EFT) on Friday to Vice-Chancellor Prof Dr Hassan Amir Shah at a ceremony, which was also attended by EFT Executive Committee Se ugg boots f眉r damen cretary Dr Khalid Manzoor Butt.The trust would initiate a perpetual gold adidas campus en scholarship from the donation that would be given to an orphan student every year on merit and would fully cover their university fee and hostel dues.A few months ago, 82-year-old eminent poet and distinguished professor of Persian language, Prof Dr Zaheer Ahmed Siddique, had set a highly inspiring precedent of generosity by donating his land worth approximately Rs 140 million and Rs5 million of lifetime savings to the GCU-EFT for scholarships of underprivileged students.VC Dr Hassan said nations the world over had pr

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ISLAMABAD:Chief Justice of Pakistan (CJP) Justice Mian Saqib Nisar has expressed displeasure on the final investigation report of the ongoing Tayyaba torture case, saying s ugg boots damen everal aspects were yet to be explained.The country鈥檚 top judge regretted how the police report failed to explain the loopholes in the 鈥榗ompromise鈥?acquired newbalance 550  and approved under questionable circumstances; hasty handover of the child maid, and the counsel's suspicious role in this regard.Tayyaba was employed by Additional District and Sessions Judge Raja Khurram Ali Khan at his house in Islamabad. The judge and his wife, Maheen Zafar, are accused of keeping the girl in wrongful confinement, burning her hand, beating her with a ladle, detaining her in a storeroom, and threatening her with even worse.New revelations make child maid case murkierThe story of the juvenile maid was picked up by the media after it went viral on social media on December 29. Subsequently, the police registered a case, adidas samba adidas  while the Islamabad High C Ductal carcinoma in situ (DCIS) is a precursor of breast cancer where the cancerous cells are contained within the milk-making ducts. Without treatment, commonly a combination of breast-conserving surgery and radiotherapy, up to a half of patients will have their disease come back, either as DCIS or as invasive breast cancer.It is currently not possible to predict which cases will progress; so all women are offered radical treatment, potentially unnecessarily.A recent study by researchers from the Manchester Cancer Research Centre, published in the journal Annals of Oncology, has explored potential subtypes of DCIS and whether these subtypes relate to dise nike dunk low ase recurrence.Professor Nigel Bundred, from The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, who led the study, said: 鈥?dunk nike low We know that different subtypes of invasive breast cancer have different levels of disea dunk high se recurrence. We wanted to investigate similar subtypes in DCIS to see if they ha

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KARACHI:The birth of three cubs at the Karachi Zoological Garden on Friday cheered the staff mourning the demise of the 16-year-old Bengal tiger the same day.According to Karachi zoo deputy director Abida Raees, the female cougar, named Vinee, was in labour for around ten hours. The staff decided to let Vinee give b adidas campus irth naturally despite the long labour period, informed the chief security guard of the zoo, Suleman Sajjad."The mother and young ones are fi adidas campus verte ne now," said Raees, adding that the entire staff got excited aft adidas campus nere er the arrival of the three cubs.Five cheetah cubs fight for survival after rare C-section birthThe cubs cuddled their mother with their eyes closed while Vinee was licking their heads, the moment was captured in a video recorded by Sajjad on his mobile phone just after Vinee gave birth.Vinee has been separated from her male counterpart, Cuba, said Raees adding that they wanted the female puma to devote all her attention to the cubs. "If we would have left Cuba in the cage Evotec AG announced that it has signed an agreement with AstraZeneca in the field of kidney diseases.Under the terms of this licence and collaboration agreement, AstraZeneca will receive access to a selected series of molecules identified in a screening effort, which is part of Evotec鈥檚 systematic kidney disease initiative. This particular programme has been d nike dunk low esigned to explore a key mechanism in the field of chronic kidney disease. AstraZeneca will provide industrial scope and scale as well as pharmaceutical development expertise and marketing capabilit yeezy 500 ies.The agreement between Evotec and AstraZeneca t dunk nike low riggers an undisclosed upfront payment as well as pre-clinical, clinical and regulatory milestones. Evotec is also eligible for additional milestone and royalty payments related to commercialisation. Evotec will receive research funding for work that will be conducted in collaboration with AstraZeneca. Specific financial details were not disclosed.Dr Cord Dohrmann, Chief Scientific Offic

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  Some people are experts at flirting. Others of us never flirt or fail spectacularly. But what kind of flirting works best?One particular flirting technique almost always works for everyone and in every situation. More on that later, because not everything works every time.鈥淲hat鈥檚 mos newbalance schuhe t effective depends on your gender and whether the purpose of the flirtation is a long-term or short-term relationship,鈥?says Leif Edward Ottesen Kennair, a professor at the Norwegian University of Science and Technology's (NTNU)Department of Psychology.Kennair belongs to a research group that has  nb studied flirting i adidas yeezys n Norway and the USA and what people believe are effective tactics 鈥?and for whom and in what context.The research group came from NTNU and from Bucknell University in Pennsylvania and State University of New York at Oswego.We flirt鈥?well, because of thisBut first: What exactly is flirting?鈥淔lirting involves different signals that people send to each other. It鈥檚 done to attract potential partners  LAHORE:Bar associations have called for the constitution of a committee consisting of superior court judges to probe the recent suicide attack at Quetta鈥檚 Civil Hos adidas samba homme pital in which 70 people were killed. Speaking at a general house meeting of the Lahore High Court Bar Association on Friday, lawyers鈥?representatives said the attack in Quetta was an attack on the state of Pakistan. They said that by targeting soft targets, the terrorists wanted t adidas campus verdi o spread fear in the public and to sabotage law and order. They said Pakistan鈥檚 enemies were not in favour of the China-Pak Economic Corridor (CPEC) projects. That was why they were trying to create unrest in Balochistan, the speakers said. The meeting was arranged to brief the house about the visit of an LHCBA delegation to Quetta. The delegation said they had visited the families of the deceased and the injured and held meetings with the provincial go samba adidas vernment representatives.Published in The Express Tribune, August 13th, 2016.

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  In 2018, the Hamburg life science company is presenting its highly prestigious research prize for the 23rd time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn selected Prof. Dr. Andrea Ablasser, Assistant Professor at the Swiss Federal Institute of Technology, Lausanne, Switzerland, as the 2018 winner of the Eppendorf Award for Young European Investigators.The Award ceremony took place at th converse all star e EMBL Advanced Training Centre in Heidelberg, Germany, on June 21, 2018. The laudatio honoring Andrea Ablasser鈥檚 achievements was held by Award Ju yeezy schuhe ry Chairman Prof. Reinhard Jahn of the Max Planck Institute for Biophysical Chemis yeezy slides try, G枚ttingen.Andrea Ablasser, born 1983, receives the 鈧?20,000 prize for her contributions to a key step in the innate immune response, which triggers a frontline defense when cells are attacked by microorganisms.  The Jury: 鈥淎ndrea Ablasser鈥檚 work sheds light on the mechanisms by which other cells are informed about the presence of foreign DNA, and s  New Delhi is planning to slow down the issuance of visas to Pakistani applicants聽in retaliation to Indian spy Kulbhushan Jadhav's death sentence, the Indian Express聽reported.Artists, singers and actors are likely to be the first group to be singled out for maximum impact.The initial plan was to block visas for all Pakistani nationals, sources told the聽Indian Express. However, India is 'testing' waters by targeting 'high-visibility' groups to gauge the effect of the move.Pakistan followed due legal process in Yadav's trial: adidas samba adidas  Khawaja AsifThe government is also con adidas samba rose templating the idea of placing a blanket ban. However, they acknowledge it will be difficult to implement because students and patients require humanitarian intervention.鈥淭he present situation, after Yadav鈥檚  stanleycup sentencing, is going to get worse. The missions will have to work with depleted strength for some more months now, it seems,鈥?said sources.The Indian government is also allegedly exploring a number of diplomatic and non-diplo

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  It is often maintained that genetic interventions may h new balance 9060 ave unintended consequences for the metabolism of modified plants and by implication for human health and the environment as wel new balances 530 l. A recently completed research project compared gene expression and plant substances in different conventional and transgenic barley lines. GMO Safety discussed the findings with Uwe Sonnewald, one of the project leaders.GMO Safety: What were the aims of your research project?Uwe Sonnewald: In our joint project with the University of Giessen and the State University Washington we aimed to test the extent to which different varieties o jordans damen f barley differ from one another, the extent to which transgenic and non-transgenic barley plants differ from one another and the impact of environmental factors. To this end we studied gene expression in the plants and the composition of the metabolites, i.e. the metabolic products. We originally intended to study the leaves and the grains but as it turned out we were unabl  The ultimate question for ardent DC Comics fans is not: Who鈥檚 stronger among Superman and Batman, or who鈥檚 faster? Because obviously, Superman wins both cases. He can fly, shoot heat rays from his pupils, scan through solid concrete, and is virtually invincible against bullets. Basically, Superman possesses the potential to beat Batman in just about every capacity. Some would say he鈥檚 even better looking, or stanley shop  more of a gentleman for that matter.The real question here is, which of these super heroes would win in a fight? In this case, not-so-surprisingly, the caped vigilante with the strange voice evens the score. According to Entertainment Weekly, the odds are in Batman鈥檚 favour because he always thinks and plans ahead. Instead of pulling out all the guns and blindly throwing punches i adidas sambarose n the air, the Bat studies, analyzes, does hi new balance donna s bit of research and then proceeds to devising a cunning plan. Finally, he steps into the arena to fight his opponent.In the upcoming Batman v Superman: Dawn o

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KARACHI:KARACHI. The rupee was stable ag adidas campus 00's ainst the dollar at 104.45/104.65 in the inter-bank market on adidas samba uomo  Wednesday compared to Tuesday鈥檚 close of 104.45/104.65. The currency market has fluctuated regularly in recent months with hefty rises and falls on some occasions. In the long run, however, the rupee has stood firm after experiencing extensive volatility, when it weakened from around Rs98 to a dollar to above Rs103 in the wake of political impasse over alleged election rigging. Earlier, the rupee remained glued to the Rs98 level for months, recovering from the historic low of Rs110. It came u newbalance 530 nder pressure following heavy debt repayments to the International Monetary Fund (IMF) and other creditors, which ate into the central bank鈥檚 foreign currency reserves. In 2013-14, the reserves, however, swelled more than 50%, thanks to IMF and other assistance and growing remittances sent home by overseas Pakistanis.Published in The Express Tribune, December 8th, 2016.Like聽Business on Facebook, fo Geron Corporation鈥檚 telomerase inhibitor cancer drug, GRN163L, has demonstrated good pharmacokinetics and tolerability in its ongoing Phase I/II trial involving patients  dunk high with chronic lymphocytic leukemia (CLL), according to data presented by Alan Colowick, M.D., M.P.H., the company鈥檚 president, oncology, at the Pan Pacific Lymphoma Conference in Maui, Hawaii.A pharmacokinetic analysis of three patients in the highest dose cohort (cohort 4, 160 mg/m2 IV/week) has shown transient peak plasma concentrations of GRN163L of approximately 10 ug/ml. This and other data indicate that the drug continues to exhibit favorable pharmacokinetic properties that are linear with respect to the doses test dunk cacao ed so far.Up to the current dose levels, no significant changes in telomerase activity or telomere length in the bulk circulating CLL cells of treated patients have been observed. These pharmacodyn nike air forces 1 amic results are consistent with expectations because of the relatively short exposure of CLL cells in patie

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Pakistan should respond to India鈥檚 latest moves on the Indus Waters Treaty (IWT) in a responsible manner aimed at achieving its core concerns over the shared w adidas samba negras ater resources of the Indus Basin, its sole source of fresh water. In this regard, an analysis of the decisions taken by a high-level meeting convened by Prime Minister Modi on September 26 is called for. In the absence of an official statement, we have to rely on the summary of the outcome of the meeting carried by The Hindu on September 27.Indian prime minister reviews Indus Waters TreatyHappily, India has decided to neither seek a review of, nor abrogate, the IWT amid speculations in the Indian media on the likely renunciation of the agreement that has survived three wars and recurring tension between India and Pakistan since it was signed in 1960.India鈥檚 decision to utilise 鈥渢o the fullest possible extent鈥?its share of waters under the Treaty is unexceptionable but innocuous. The IWT gives India the t nb 550 hree e new balance uomo astern rivers for u ThermoGenesis Corp. has announced that its devices will be the subject of several scientific abstracts to be presented at the International Stem Cell Therapy (ISCT) 2009 Annual Meeting in San Diego, May 3-6.The abstracts will cover the efficacy of the Company's BioArchive庐 System, MarrowXpress鈩?(MXP鈩? and Res-Q鈩?devices in the processing of stem cells from cord blood and bone marrow.Additional abstracts will address the impact of sterilization practices on stem cell dunk nike low  processing, and findings regarding the collection of equine stem cells. The Company will also be demonstrating its products at booth #200."We are delighted to have the opportunity to contribute to this leading stem cell industry conference. We bel adidas yeezy ieve this foru yeezy slide m provides us the opportunity for the industry to be aware of the value of our devices in the collection and storage of stem cells from cord blood and bone marrow, as well as our ability to bring innovation to the market through devices such as the MXP and Res-Q," sai

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  For decades, researchers have tried to duplicate the function of beta cells, the tiny insulin-producing entities that don鈥檛 work properly in patients with diabetes. Insulin injections provide painful and often imperfect substitutes. Transplants of normal beta cells carry the risk of rejection or side effects fr tenis yeezys om immunosuppressive therapies.Now, researchers at the at Chapel Hill and North Carolina State University have devised another option: a synthetic patch filled with natural beta cells that can secrete doses of insulin to control blood sugar levels on demand with no risk of inducing hypoglycemia. The proof-of-concept builds on an innovative technology, the 鈥渟mart insulin patch,鈥?reported last year in the Proceedings of the National Academy of Sciences.Both patches are thin polymeric squares about the size of a quarter and covered in tiny needles, like a miniature bed of nails. But whereas th nike store dunk e former approach filled these needles with manm yeezy 700 ade bubbles of insulin, this new 鈥渟mart cel  It is common knowledge that Bollywood superstars Shah Rukh and Salman share an on-and-off relationship.The two have been publicly rooting for one another after burying the hatchet. In an interview to聽Femina, King Khan spoke about how no one can聽complete with Salman at the box office while g adidas samba sale iving聽his two cents on a range of topics.Salman Khan and I are brothers: Shah Rukh Khan"Let鈥檚 look at it like this. I can鈥檛 compete with Salman Khan at the box office; none of us can. That is the reality," the聽Raees star said.When queried on the pay disparity between male and female actors in Bollyood, Shah Rukh spoke about the indelible impact his co-stars Madhuri Dixit Ne adidas samba schuhe ne, Kajol and Juhi Chawla had left on him. "Mad ugg boots tasmania huri, Juhi and Kajol are such beautiful women and wonderful actors. I鈥檓 a star because of them; they鈥檝e taught me all that I know," he said.Diplomatic: Shah Rukh Khan mum over Salman Khan鈥檚 rape comment"I know women actors work five times harder and get paid 10 times less than men. I a