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  Cleveland BioLabs, Inc. has announced that it has accumulated preclinical data demonstrating that CBLB502, a drug under development to treat exposure to radiation, has direct anticancer effect in several transplanted cancer models grown in mice and rats including colon and lung cancer, lymphoma and melanoma. In one of the animal models of transplanted colon cancer, CBLB502 treatment resulted in complete tumor regression with no recurrence of the disease in a large percentage of animals.Experimental results suggest t baskets yeezy hat CBLB502's anticancer effect stems from the same mechanism which underlies its ability to treat radiation exposure and which involves tissue-specific activation of innate immune response mediated by CBLB502's interaction with its receptor, TLR5. Antitumor effects largely depend on the  nike high dunk expression of TLR5 by the tumor.However, in the case of tumors residing in the liver, the organ which has been identified as the natural primary ta air force schwarz rget site for CBLB502 activity, tumors beco  NAIROBI:Kenyan President Uhuru Kenyatta maintained his strong lead in the presidential election cou adidas samba nera nt on Wednesday with 85 percent of polli adidas samba bianche ng stations reporting, the election commission said.Kenya's keenest voter braves old age, rain to make her markIts website showed Kenyatta with 54.8 percent of the vote against 44.3 percent for opposition leader Raila Odinga, a margin of nearly 1.4 m new balance nere illion votes.

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Left-arm fast-bowler Wahab Riaz was struck by a throw between his neck and right shoulder and had to be taken to a hospi adidas campus 80s tal for a scan.However, the team management has confirmed that Wahab鈥檚 scans came out clear a nb balance nd he is available for selection against New Zealand.Pakistan face rampant Black Caps in must-win match鈥淲ahab was struck by a stray throw during the fielding session and his scans were taken as a precautionary measure,鈥?Paki adidas samba rose stan media manager Agha Akbar told The Express Tribune. 鈥淗e is ok and will be available for selection against New Zealand.鈥滿eanwhile, fellow pacer Mohammad Amir was given a rest so that he could recharge his batteries for the matches against New Zealand and Australia.Pakistan face NZ in must-win encounterA resurgent New Zealand will be eyeing a semi-final berth when they take on a deflated Pakistan in a World Twenty20 group match in Mohali Tuesday.Smarting under a six-wicket defeat to arch rivals India, Shahid Afridi's men need a victory against the table-t In five-year-old children, the risk for being overweight is almost twice as high if they at 12 months had consumed milk cereal drinks every day, a study in the journal Acta Paediatrica shows.鈥淢ilk cereal drinks are not bad as such; how it鈥檚 used is the problem. That is, when it鈥檚 seen not as a meal but as an extra, to supplement other food,鈥?says Bernt Alm. Associate Professor of Pediatrics at Sahlgrenska Academy, University of Gothenburg.The researchers behind the study have previously linked consumption of milk cereal drinks at age six months to high body mass index (BMI) at ages one year and one and a half years. T yeezys he study now presented is of the same group of childre nike store dunk n, several years later.Various risk factorsThe follow-up study comprised 1,870 children in Halland Co asics gel unty, Sweden, whose particulars were taken from the Halland Health and Growth Study. Height and weight data have been recorded by the child health services, while the information on their food and beverage intake comes f

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HYDERABAD/KARACHI:Following the countrywide terro adidas samba vegan rist activities, security has been increased in Sindh to ensure that people celebrate Eidul Fitr without fear. As many as 10,000 police officials, along with 5,000 Rangers' personnel will guard the residents of Karachi during Eidul Fitr prayers today.Eid prayers in the metropolis will be held at more than 4,341 locations, including 3,664 mosques, 447 eidgahs and open areas, and 230 imambargahs and jamaatkhanas, out of which 50 locations have been declared 'sensitive'. The  zapatillas nb main congregations will be held at the old Polo Ground, Nishtar Park, T-Ground in Federal B Area, and Nazimabad Eidgah. All these places will be swept for explosives and cleared before any congregations gather."Around 9,135 policemen, including officers, will be performing special duties on the three days of Eid to maintain the law and order situation," reads a statement issued by the Central Police Office (CPO). "Other than this deplo adidas campus rouge yment, personnel from six platoons  Ne yeezy 350 w researc dunk nike store h from Yale School of Medicinepublished inCell Metabolismsuggests that pregnancy accelerates aging, but with an important caveat鈥攖here appears to be significant reversal of this effect in the postpartum period.To make this discovery,Yale Child Study CenterAssistant ProfessorKieran O鈥橠onnell, PhD,and his team made use of a unique pregnancy cohort that provided epigenetic data across pregnancy, allowing them to calculate measures of biological aging using 鈥榚pigenetic clocks.鈥橣rom early to late pregnancy, a period of approximately 20 weeks, biological 鈥?or epigenetic 鈥?age increased by approximately two years, suggesting that pregnancy does indeed accelerate aging. However, when O鈥橠onnell and his team examined biological age in the same women three months later, what they saw came as surprise.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, asics outlets  delivering breaking science news straight to your inbox every day.Subscribe for FREE

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  Some memory devices where information from smartphones and computers is stored are based on a very precise control of the magnetic properties, at nanoscopic scale.  dunk nike high The more precise this control is, the more storage capacity and speed they can have. In certain cases, the combination of ferromagnetism (where the magnetism of all the atoms in the material po adidas yeezy ints in the same direction) and antiferromagnetism (where the magnetism of the atoms in the material points alternately in opposite directions) is used to store the information. One of the materials that can show these two arrangements is the alloy of iron and rhodium (FeRh), because it shows a metamagnetic transition between these two phases at a temperature very close to room temperat dunks nike low ure. In particular, it can change state from antiferromagnetic to ferromagnetic simply when heated. The antiferromagnetic state is more robust and secure than the ferromagnetic one, since it is not easily altered by the presence of magnets in its proximi  ISLAMABAD:The National Police Bureau, in collaboration with the Research Society of International Law (RSIL) and the International Committee for the Red Cross (ICRC), have launched a compendium of frequently used laws and procedures.The compendium, titled 鈥淔requently Applied Police, Laws and Criminal Procedures: An Abridged Compendium鈥? includes relevant police statistics, legal abbreviations, police procedures and laws.It entails pertinent anti-terrorism laws, special laws, the Constitution and rules of business. Additionally, it includes FIR, investigation and trial procedures.It also has section samba adidas s on the use of force by law enforcing agencies, preventive detention and human rights obligations.The objective of the compendium is to collate frequently applied sections of laws and rules in one book for conve adidas samba bianche nient and manageable application. This compilation is expected to be dispatched to 1,836 p nb balance olice stations, 115 district SSPs, DIGs, prosecution services, prisons and concomitant depart

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  Starpharma Holdings Ltd today announced the signing of an agreement with global pharmaceutical company AstraZeneca giving Astr asics gel 1130 aZeneca the right to test certain proprietary Starpharma oncology molecules based on Starpharma鈥檚 dendrimer techn adidas yeezy ology. The primary objective of the program is to assess the suitability of the dendrimer constructs for particular applications within the cancer field.The identity of the anti-cancer molecules to be studied is covered by confidentiality restrictions, but Starpharma notes that the arrangement does not relate to docetaxel or to dendrimer conjugates of docetaxel. Further details of the arrangement between the parties were tenis yeezys  not disclosed.  Singer Rihanna, who is acting in Valerian聽and Ocean's Eight, says while nobody works especially to win awards like Grammies or Oscars, it's always nice to get some validation.She spoke about her new life as an actor in an interview with the The Sun on Sunday. "I'd love to get there one day. Who doesn't want to be told they are doing a great job? Any validation that your work is impacting is rewarding. I work hard adidas samba adidas  and put my all into everything I do but the rest isn't up to me," asserted the Diamonds singer.When Chris Brown kept texting RihannaRihanna went on to say, "I don't think anyone makes an album thinking abo adidas campus noir ut winning a Grammy, or makes a movie thinking about winning an Oscar. What you do is work as hard as you can and if awards follow,  uggs hausschuhe then that's great."Rihanna plays shape shifting entertainer Bubble in Valerian. Though she didn't method act for the movie, she finds it interesting. "It's pretty difficult to method act when it comes to playing a shape-shifting entertainer but,

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Bjos Rare Skin Disease Gene Uncovered
HYDERABAD:The whereabouts of adidas samba  a journalist and his two relatives who were whisked away on August 4 from their residences in Jamshoro district remain unknown, despite the family cont adidas samba vegan inuing protests for their return for a month.Ghulam Rasool Burfat, a sub-editor at a Sindhi daily, his cousin and National Bank of Pakistan officer Zaheer Hussai adidas campus donna n Burfat and their nephew Asif Burfat were allegedly taken away by a law enforcement agency.All of them are family members of self-exiled nationalist leader Shafi Muhammad Burfat, who heads the banned Jeay Sindh Muttahida Mahaz party. Dozens of female members and children of the family held a protest on Wednesday outside the Hyderabad Press Club carrying photographs of the three missing men.Protest held against missing persons on Super HighwayMumtaz Burfat, wife of Ghulam Rasool and sister of Shafi Muhammad, who led the protesters, appealed to the LEAs to show mercy on their family members and release them. "They have never been involved in any crimin Since its invention over 400 years ago, the microscope has continued to evolve, peering ever deeper into chanclas yeezy  nature鈥檚 mysteries at the smallest scales.In new research, Prof.Shaopeng Wang, his postdoctoral research scholarGuangzhong Maalong with their colleagues at theBiodesign Center for Bioelectronics and Biosensorsat Arizona State University describe advances in microscopy based on a phenomenon known as surface plasmon resonance (SPR).The new study highlights a series of experiments th nike dunk high at show how SPR technology can be used to precisely image 100 single molecules simultaneously and describe their dynamic activities in real time, particularly when molecules bind with each other and carry out important biological functions. 鈥淭aking advantage of the extremely high sensitivity in the axial (vertical dunks nike store ) direction, SPR can track the particle's axial motions with sub-nanometer precision, which is much more precise than regular microscopy imaging,鈥?Wang says. 鈥淲e demonstrated that this feature can

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KARACHI:We need to work on Karachi development plan, said Mayor Wasim Akhtar while talking to the media outside Sindh Assembly on Friday. He requested the chief minister to reconsider the government鈥檚 decisi adidas samba  nb 550 on and empower the local bodies. 鈥淭he CM is an educated person and I hope he will resolve this issue,鈥?he said, adding that Karachi has turned into a garbage dump and local bodies鈥?elected representatives are powerless. 鈥淚 am thankful to Bilawal Bhutto for raising voice against my arrest,鈥?he said. Earlier, the mayor held a meeting with Sindh Assembly speaker Agha Siraj Durrani and former CM Qaim Ali Shah. The elected representatives of both the parties were also present on the occasion. The speaker presented a shield to the elected mayor.Published in The Express Tribune, N stanley ovember 19th, 2016. Artel, the worldwide leader in liquid handling quality assurance, announced it will conduct a hands-on workshop on Best P nike dunk high ractices in Automated Liquid Handling at the Tecan US headquarters in Durham, North Carolina. Tailored for lab technicians who work with automated liquid handlers on a regular basis, the October 28 workshop will utilize state-of-the-art liquid handlers and Artel performance measurement technology, to help attendees work through - and solve - common, but critical issues affecting liquid handler performance.Using the Artel MVS庐 (Multichannel Verification System), Artel application specialists will lead the workshop, focusing not only on how to identify and resolve problems, but also on how to develop and optimize liquid handler quality programs.Attendees will be able to explore and master methods to get the maximum performance out of their liquid handler for assay specific situations. After collecting objective data a yeezys nd ana nike dunk high lyzing and interpreting the results, workshop

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Ixie Cell Types Vulnerable in Multiple Sclerosis Are Identified
  The fate of the world's coral reefs could depend on how well the sea creatures equip their offspring to cope with global warming.About half the world's coral has been lost due to warming seas that make their world hostile. Instead of vivid and floral, coral bleach pale as temperatures rise. This happens because the peculiar animal cohabitates with algae, which expel under stress. When that happens, coral lose their color and a life partner that sustains them, so they starve.Yet, hope occurs in aquariums at the USC campus near downtown Los Angeles and at the Australian Institute of Marine Science. There, biologists study coral's unusual ability to shuffle their so-called symbionts -- the algae colonies inside their cells -- as a coping mechanism to potent yeezy 350 ially gain an advantage in a changing environment.For the first time, the researchers have shown that adult coral can pass along this ability to shuffle their symbionts to the dunk homme ir offspring. It' dunks s a process that occurs in addition to tradi  Allama Iqbal Open University (AIOU) will expand research work on gender studies in order to give academic support to women empowerment.This was stated by the Vice Chancellor Dr. Shahid Siddiq nb ui while addressing the concluding session of聽 first-ever national conference on gender studies that was held to promote academic research, relating to women鈥檚 role and contribution in the country鈥檚 socio-economic development.Capacity building: Project on gender studies launched at AIOUHe announced they will soon publish a research journal on gender and women st ugg fellboots udies to promote the cause of women. Such event will be an annual feature, campus adidas  and next year an international conference will be organised to construct and disseminate knowledge so as to enhance respect and social status of women.Gender and women studies attempts to expand the definition and perceptions of existing gender dynamics between women and men in the society.Published in The Express Tribune, August 13th, 2017.

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  A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for  nike sb dunk the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors.The researchers focused on the area of the brain called hippocampus, which plays an important role in learning and social interactions; and synapses, which are specialized contacts between neurons.Each n asics schuhe euron in the brain receives numerous excitatory and inhibitory synaptic inputs. The balance between excitation yeezy femme  and inhibition in neuronal circuits, known as E/I balance and thought to be essential for circuit function and stability and important for information processing in the central nervous system, can play a role in causing many neurological disorders, including epilepsy, autism spectrum disorder, and schizophrenia.The researchers also focused on a protein called ephrin-B1, which spans the membrane surrounding the cell and plays a role in main  LAHORE:The 969-megawatt Neelum Jhelum Hydropower project is progressing timely as the civil works of the both the underground powerhouse and transformers hall are 95.5% and 99% complete, respectively, and are expected to finish in October this year.This was briefed to Pakistan Water and Power Develop boots kaufen ment Authority (Wapda) Chairman Zafar Mahmood during his weekly visit to the project site.Neelum Jhelum: First unit to be commissioned in June 2017The chairman visited the powerhouse, transformers hall, manifold area and  newbalance 530 switchyard of the project to review progress of construction work. Neelum Jhelum Hydropower Project Chief Executive Officer Engineer Muhammad Zubair, Project Director Nayyar Alauddin and representatives of the consultants and contractors were present on the occasion.During the on-site briefing, the chairman was apprised that subsequent to the completion of civil works of unit No3 and 4 of the powerhouse, both units had already been handed over to the e newbalance scarpe lectro-mechanical cont

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Toqy 4 worst and best moments from Grammys 2017
  What clues does our memory use to connect a current situation to a situation from the past? The results of a study conducted by r yeezy slides esearchers from the University of Geneva (UNIGE), Switzerland, - working in collaboration with CY Cergy Paris University in France - contrast sharply with the explanations found until now in the existing literature. The researchers have demonstrated that similarities in structure an yeezy schuh d essence (the heart of a situation) guide our recollections rather than surface similarities (the general theme, for example, or the setting or protagonists). It is only when individuals lack sufficient knowledge that t asics hey turn to the surface clues - the easiest to access - to recollect a situation. These results, published in the journal Acta Psychologica, are particularly relevant in the field of education. They underline the need to focus on the conceptual aspects of situations that are tackled in class to help pupils make use of the relevant features, and not to be misled by a  LAHORE:Experts have underscored the dire need for maintaining a balance between revenues and expenditures as budget deficit forces the government to resort t adidas campus donna o borrowing that eats up a major part of the federal budget.Tax and structural reforms and broadening of the tax net are the most appropriate solutions to this challenge.Experts from the trade, industry and academia expressed these views while speaking at a post-budget seminar organised jointly by the Lahore Chamber of Commerce and Industry and the Institute of Cost and Management Accountants of Pakistan on  new balance bleu Tuesday.They insisted that businesses required incentives and facilitation for growth as industries were facing multifarious challenges including stiff competition from regional countries and power load-shedding at home.However, the major bottleneck was the unfriendly tax system, they said while pointing out that the industry contributed 76% to the tax revenues while agriculture had a share of j stanley store ust 2%. The rest came from the ser