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Kszt Scientists Uncover Brain Circuits Behind Putting up a Fight or Freezing
THAILAND:It wasn't until he got to medical school that Narong Khuntikeo finally discovered what caused the liver cancer that took both of his parents' lives: their lunch.Like millions of Thais across t adidas samba schuhe he rural northeast, his family regularly ate koi pla - a local dish made of raw fish ground with spices and lime.The pungent meal is quick, cheap and tasty, but the fish is also a favourite feast for parasites that can cause a lethal liver cancer killing up to 20,000 Thais annually.Most hail from northeast, a ugg hausschuhe  large, poor region known as Isaan that has dined on koi pla for gener adidas samba adidas ations and now has the highest reported instance of the Cholangiocarcinoma (CCA) - bile duct cancer - in the world.One of the major causes of CCA is a parasitic flatworm - or fluke - which is native to the Mekong region and found in many freshwater fish. Once eaten, the worms can embed undetected in the bile ducts for years causing inflammation that can, over time, trigger the aggressive cancer, according to the Wor Sci dunk low entists at the University of Liverpool have discovered a new and important function of a toxin produced by disease-causing bacteria that could have significant implications for future vaccine design.Streptococcus pneumoniae (the pneumococcus) is a major cause of life-threatening invasive diseases such as pneumonia, septicaemia and meningitis, and is responsible for more than one million deaths every year. Key to its disease-causing success is the action of a potent toxin called pneumolysin, which works by creating 鈥榟oles鈥?in the membranes of human cells, and either killing them directly or causing significant tissue damage.Until now, scientists believed that the effects of pneumolysin resulted purely from the binding of the toxin to cholesterol in host cell membranes. A new study published in Nature Microbiology, however, shows that pneumolysin ca asics gelkayano n also bind directly to a host cell receptor on specialised immune cells to suppress the immune response new balance 550 .The study was a collaboration bet

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Father of Pakistan鈥檚 nucl campus adidas femme ear programme Dr Abdul Qadeer Khan has claimed that Pakistan has the ability to 'target' Indian capital New Delhi in just five minutes."Pakistan has the ability to target New Delhi from Kahuta near Rawalpindi in five minutes," Khan said.Nuclearisation of the Indian Ocean regionAddressing an event organised in Islamabad to celebrate the 18th anniversary of Pakistan's first nuclear tests, carried out under his supervision in 1998, Khan said Pakistan could have become a nuclear power in 1984, if then President General Ziaul Haq hadn't 鈥渙pposed the move鈥?"We were able and we had a plan to launch nuclea new balance 480 r test in 1 newbalance 9060 984. But President General Ziaul Haq had opposed the move," Khan said.According to Khan, General Zia believed that nuclear testing would not only result in world intervening militarily, but also affect international aid Pakistan was receiving due to the ongoing Soviet occupation of Afghanistan.Pakistan to set up first mega nuclear power plant: Ahsan IqbalYo By making use of enzymes found in the digestive tract, MIT engineers have devised a way to apply a temporary synthetic coating to the lining of the small intestine.  yeezys This coating could be adapted to deliver drugs, aid in digestion, or prevent nutrients such as glucose from being absorbed.In a study conducted in pigs, the researchers demonstrated that they c yeezy ould use this approach to simplify the delivery of medications that normally have to be taken multiple times per day. They also modified the coatings to deliver the enzyme lactase, which helps people digest the milk sugar lactose, and to block glucose absorption, which could offer a new strategy to treat diabetes or obesity.鈥淭hes yeezy slides e three applications are fairly distinct, but they offer a sense of the breadth of things that can be done with this approach,鈥?says Giovanni Traverso, an MIT assistant professor of mechanical engineering, a gastroenterologist at Brigham and Women鈥檚 Hospital, and the senior author of the study.The lining consi

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  Pairing blueberry pie with a scoop of ice cream is a nice summe tenis yeezys r treat. Aside from being tasty, this combination might also help people take up more of the 鈥渟uperfruit鈥檚鈥?nutrients, such as anthocyanins. Researchers reporting in ACS鈥?Journal of Agricultural and Food Chemistry show that 伪-casein, a protein found in cow鈥檚 milk, helped rats  air force 1 absorb more blueberry anthocyanins and their byproducts, boosting accessibility to these good-for-you nutrients.In studies, anthocyanins have been shown to have antioxidant properties, lower blood pressure and reduce the risk of developing some cancers. However, only small amounts of  yeezy 350 these nutrients are absorbed from blueberries during digestion, despite their abundance in the fruit. Previous researchers have reported that consuming foods with ingredients such as citrus pectin, capcasin, capsicate and some proteins improve the uptake of anthocyanins. For instance, Bin Li and colleagues found that 伪-casein and 尾-casein proteins from cow鈥檚 milk protected  KARACHIeshawar has had its share of being in the news for all the wrong re new balance uomo asons in the past few years but that has changed in recent months, with the city  adidas campus rose now showing signs of recovering from the damaging effects that came along with the war on terrorism.That recovery also saw the rise of a venture whi newbalance 550 ch came to the fore with much anticipation and played a crucial role in shepherding the cricketing fan-base in the city; Pakistan Super League (PSL) franchise Peshawar Zalmi.How Islamabad United are helping Pakistan cricketZalmi made the loudest bang among all the teams in the PSL and soon boasted a strong fan-following on the back of star signings such as Shahid Afridi and Darren Sammy, both of whom played a crucial role in the team鈥檚 journey to the playoffs in the first edition and then the final in the second.While that was what was happening on the pitch, Zalmi have been quite active off it as well.Franchise owner Javed Afridi, while talking to The Express Tribune, talks about how Z

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  R adidas yeezys esearchers have discovered a promising new strategy for combating malaria, a mosquito-borne parasite that claims nearly a half-million lives each year.For a study reported in the journal Nature, researchers screened blood samples from children who had natural immune resistance to severe malaria infection. The study identified an antibody to a particular malaria protein, calle yeezy 500 d PfGARP, that appears to protect resistant children from severe disease. Lab tests showed that  asics gel antibodies to PfGARP seem to activate a malarial self-destruct mechanism, causing parasite cells living inside human red blood cells to undergo a form of programmed cell death.The team is hopeful that vaccinating individuals with PfGARP to generate anti-PfGARP antibodies, or directly infusing anti-PfGARP antibodies, would protect them against severe malaria. The team developed preliminary versions of those vaccines, and testing in nonhuman primates has shown promise, the researchers report."We demonstrated in two indepe  ISLAMABAD:Nadra has sacked over 600 of its employees for 鈥榠llegally鈥?issuing CNICs to 160,286 aliens or non-residents of the country, Nadra Chairman Usman Mobin told the Senate鈥檚 Functional Committee on Less Developed Areas on Thursday.鈥淲e have removed over 600 employees after conducting several inquiries into the illegal issuance of CNICs to aliens,鈥?Mobin shared before the committee with Senator Mir Kabir in the chair.To a question raised by Senator Nisar Muhammad as to who were the employees involved in such affairs, Mobin replied that more than 500 were data entry operators.WikiLeaks tweets reminder that 'US and UK had stolen NADRA records'When the committee was informed that minimum salary of such operators was Rs12,000 per month, Muhommad asked Mobin, 鈥淲hat salary are you earning chairman?鈥漈he Nadra chief reluctantly replied, 鈥淩s800,000.鈥漈he senators said with one v zapatillas nb oice, 鈥淲hat else could be expected from poor operators  adidas campus beige who draw such a mea ugg boots gre salary, while their senior enjoys such

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Pzki DNA Origami Packed Full of Potent Anticancer Agents
  D claquette yeezy eveloping low emission vehicles of the future will be the focus of a major collaboration launched by the Malaysian Deputy Prime  yeezy slide Minister at Imperial College London.Mr Tan Sri Muhyiddin Yassin, Malaysia鈥檚 Deputy Prime Minister and Education Minister, visited Imperial to help launch a low carbon transport research centre: a collaboration between the College and Universiti Teknologi Malaysia (UTM), one of Malaysia鈥檚 leading universities.The UTM Centre for Low Carbon Transport will bring together some of UTM and Imperial鈥檚 world-class researchers as they develop dunk panda  the next generation of low carbon transport technologies.The researchers will work on a range of areas to make cars more efficient, which will include reducing the size of engines to improve efficiency without sacrificing performance.Teams will look at ways of optimizing technologies for advanced hybrid and electric vehicles to improve their range. They will also develop new concepts for energy storage and waste energy recovery te  KARACHI:Two men were shot dead by unidentified assailants in separate firing incidents in  stanley kaufen Korangi and Gulshan-e-Iqbal on Thursday.A Pakistan Army soldier was shot and killed by gunmen in Rahimabad, Korangi, within the limits of Zaman Town police station. The deceased was identified as 27-year-old Irfan Ali, son of Muhammad Yasin. Police officials, however, do not believe that it was an act of targeted killing.Ahmadi doctor shot dead in KarachiSHO Shahjah adidas campus noir an Lashari said that the incident took place when at least two armed men were trying to escape on a motorcycle after looting a woman, while some people were trying to catch them. While fleeing, the suspects opened fire due to which Yasin, who was in a rickshaw nearby, was shot and killed.The body was taken to Jinnah Postgraduate Medical  adidas campus donna Centre for medico-legal formalities. According to the police, the deceased was a resident of Azad Kashmir and came to Karachi to visit his in-laws. A case has been registered and further investigation is

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Vwax Change mantra fails to improve health sector
  OncoCyte Corporation, a subsidiary of BioTime, Inc., and Abcodia Ltd. have announced their collaboration focused on the development of OncoCyte鈥檚 blood-based PanC-Dx鈩?test for early detection of breast cancer.PanC-Dx鈩?is a class of non-invasive cancer diagnostics based on OncoCyte鈥檚 proprietary set of cancer markers, which were discovered by company scientists through an analysis of broad gene expression patterns in numerous cancer types. OncoCyte is currently sponsoring four clinical studies of PanC-Dx鈩?in bladder, breast, and lung cancer.Abcodia has exclusive commercial access to a unique longitudinal biobank of over 5,000,000 serum samples collected through the UK Co yeezy 350 llaborative Trial for Ovarian Cancer Screening. The biobank was derived from over 200,000 initially healthy volunteers, 50,000 of whom provided samples annually for up to yeezy  10 years.  nike air forces Since first recruitment, more than 3,700 individuals have been diagnosed with breast cancer, which generates opportunities to assess serum bi  KARACHI:A greater number of trucks plying along the Ch adidas campus 80s ina-Pakistan Economic Corridor (CPEC) are likely to be Chinese as the c stanley-cup ountry's manufacturers adidas campus donna  aim to penetrate further and gain share in a market currently dominated by Japanese players.In the recently-concluded Pakistan Auto Parts Show (PAPS) held at the Karachi Expo Centre, Chinese truck and bus manufacturers made their presence felt.German truck maker MAN SE to set up assembly plant in PakistanKeeping in mind CPEC and its need for heavy vehicles, it came as no surprise that Chinese manufacturers dominated the exhibition in terms of numbers and sounded confident over increasing their sales figures."We are looking for better sales in the coming months," said Dysin Automobile Limited Manager Tender and Commercial Sales Jawaid Iqbal.Dysin Automobiles is a regular exhibitor at PAPS and has so far sold over 700 trucks in Pakistan, informed Iqbal.Apart from the traditional sectors like oil and transport, these vehicles are being used in

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Rwrx Facilitating farmers: Food ministry for continuing fertiliser subsidy next year as well
India T20 captain Mahendra Singh Dhoni聽faced some very tough questions after his team's one-run victory over Bangladesh in Bangalore on Wednesday.One unfortunate re adidas campus orange porter came under fire after his question did not go down well with the Indian skipper known as 'Captain Cool' at the post-match press conference. stanley online shop India beat Bangladesh by one run at World T20Known for his calm and cool demeanor on field, Dhoni did not mince words when a reporter asked, "India had to win this match by a big margin to increase its net run rate, but you barely won."Interrupting him mid-question, Dhoni began, "I have just one thing to say. I know you are u adidas campus 80s nhappy that India won. Listen to me, I can tell from your tone and from your question that you are not happy with our win.""As far as cricket goes, there is no script. You have to analyse that we lost the toss and see the pitch that we had to bat on," he continued.Dhoni wasn't done yet, not by a long shot. "If, while sitting outside, you can't analyse all the r ActiveSight has announced that it has signed an agreement to provide structural biology services to Inpharmatica Ltd. asics 聽 The agreement focuses on co-crystallography by ActiveSight of certain Inpharmatica small  yeezys molecules with a human drug target protein. The agreement  asics schuhe includes upfront fees and payments for milestones."ActiveSight is delighted to augment Inpharmatica's unique drug discovery platform," stated Duncan McRee, Ph.D., President of ActiveSight.

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Hpoj Rs70 million earmarked for defence expo
KARACHI:In a coordinated move, activists and organisations working for regional peace launched the 鈥楶eace Now and Forever鈥?campaign simultaneously in various cities of India and Pakistan on Saturday.In Pakistan, the campaign was launched by the Pakistan-India People鈥檚 Forum for Peace and Democracy. The launch was held at the Karachi Press Club, where campaign founder and Human Rights Commission of Pakistan representative Asad Iqbal Butt and other activists shared details of the campaign.Butt said the campaign was conceived with the objective of addressing deteriorating relations between Pakistan and India as well as to provide platforms to enable common citizens to demand peace and condemn attempts at war mongering without being apologetic or feeling guilty about their stance.He shared that Nobel laureates nb  Malala Yousufzai and Kailash Satyarthi are also joining the campaign.Peace and development: Pakistan has made unprecedented p ugg fellboots rogress since 2013, adidas campus 00s  says ShehbazButt shared that apart fr A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease. As part of the immune system, these cells have a protective function against fibrosis and liver cirrhosis. At the same time, they are useful as biomarkers of liver disease progression a af1 s they can be measured by a blood test. The results were recently published in the renowned "Journal of Hepatology new balances 480 ".Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver  adidas yeezys diseases worldwide and is estimated to affect about 30% of the European population. Chronic non-alcoholic fatty liver disease can develop into irreversible liver cirrhosis, which can only be cured by liver transplantation. Therefore, it is particularly important to identify patients with non-alcoholic fatty liver disease early on.The pathogenesis (development) of non-alcoholic fatty liver disease, especially advanced steatohepatitis (NASH, also: non-alcoh

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  Stem Cell Therapeutics Corp. has announced that Dr. Steven Cramer of the University  new balance schuhe of California at I nike dunk high rvine will be presenting results from the REGENESIS-LED trial at the International Stroke Conference, in Los Angeles, California.The title of the poster presentation is entitled, "Study of NTx庐-265: Human Chorionic Gonadotropin (hCG) and Epoetin Alfa (EPO) in Acute Ischemic St nike high dunk roke Patients (REGENESIS Trial).""This presentation represents an important opportunity to review and discuss the modified REGENESIS trial for the first time with the stroke community." said Dr. Allen Davidoff, Chief Scientific Officer of SCT. "SCT looks forward to discussions of this trial at the meeting and integrating those discussions into our ongoing strategic planning for the NTx庐-265 program in Acute Ischemic Stroke".  BAHAWALPURolice have arrested a man accused of selling his wife for Rs200,000, 鈥渢o feed his gambling habit鈥? Saddar police said the woman鈥檚 brother had filed a complaint saying that his sister had gone missing and he believed that her husband and his father had 鈥榮old鈥?her. Police said Sajjad Ahmad, a resident of Chak 110-P, had filed a complaint saying that his 25-year-old  stanley sister had married Khan Muhammad, a resident of the same village, two years ago. He said that Khan Muhammad was a habitual gambler and was often broke. Ahmad accused Khan Muhammad and his father of selling his sister to  newbalance a man in Sindh for Rs200,000. Saddar police have a new balance 480 rrested Khan Muhammad and started investigations. They said during initial interrogation, Khan Muhammad had confessed to the crime. Police said they were looking for the other nominated suspects.Published in The Express Tribune, March 9th, 2016.

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Gssk IBM s Biomedical Analytics Platform Helps Doctors Personalise Treatment
  Queensland Compound Library (QCL) has announced the acquisition and installment of a fourth comPOUND庐 sample store from TTP LabTech Ltd.The purchasing of a fourth sample store, to integrate with their three existing comPOUND sample stores and comPANION unit, comes two years after QCL became operational and one year after the third store was added. This new purchase reflects the on-going success of QCL and the increased demand for compound management and logistics services now considered ess dunk nike ential by the Australian life sciences industry, QCL said.TTP LabTech鈥檚 comPOUN yeezy slide D sample sto yeezy sneaker re is a modular system, where individual units can be linked in parallel in response to growing library size. The self-contained modules each have their own cherry picking facility and can provide sample storage at a user defined temperature between ambient and -20掳C depending on the user鈥檚 requirements.The comPANION arrayer unit connects comPOUND stores to provide remote delivery or storage of individual micro  MADRID:Real Madrid coach Zinedine Zidane believes he has no need to rush Wales striker Gareth Bale back from a long-term ankle injury as the European champions extend adidas campus rosa ed their lead at the top of La Liga on Sunday.Bale has been out since suffering ankle ligament damage in November and is not expected to return before March.However, Zidane is hopeful of having Luka Modric and Ja stanley cup mes Rodriguez back for Real's next outing at Celta Vigo at the weekend.Ronaldo lambasts 'media campaigns' against him"Our idea to is to have Luka back next week. We adidas campus grigie  will see [how he is] on Tuesday and the same goes for James," said Zidane. "Gareth will take a while longer. He is now on the training pitch in boots which is a good sign, but we have to take it slowly."Bale is expected to miss Real's Champions League last 16 first-leg clash with Napoli on February 15 with the Welshman possibly making a return in time for the return leg on March 7.Madrid had begun to miss the Welshman's presence as they won just one of