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Zdti Scientists find huge ancient landslide on Great Barrier Reef
BANGKOK:Three Thais were killed Sunday when a train crashed into a double-decker bus carrying holidaymakers as it was crossing the line, police said.The bus was taking a group of workers from a nearby factory in Nakhon Pathom province west of Bangkok to the southern island of Koh Samui for a holiday trip, according to local police officer Thanachot Shinwongsa.At least 20 killed as flyover collapses in Indian city"Three have been reported dead, all Thais. The number of injuries is not yet confirmed," he told AFP."The scene was cleared and the train is back in service."Video footage of the accident in Nakhon Chaisri district showed the bus slow nb balance ly crossing the railway when a train ploughed into it at full speed, whipping the vehicle around.There appeared to be no lights or other warning devices at the intersection, a common failing at many unregulated railway-road junctions in Thailand.Other cars were seen  ugg boots damen driving over the tracks alongside the bus  adidas samba schuhe just seconds before the collision.Tragedi Astex Pharmaceuticals, Inc. has announced that interim Phase 1/2 clinical data from subcutaneous SGI-110, a novel hypomethylating agent, demonstrated differentiated PK profile, good tolerability, and preliminary promising complete responses in heavily new balances 530  pretreated acute myelogenous leukemia (AML) patients enrolled in the Phase 1 segment of the trial.The data was presented at an oral yeezy slide  session at the American Association for Cancer Research (AACR) 201 converse chucks 2 Annual Meeting in Chicago, IL and was featured in a joint AACR-Stand Up To Cancer (SU2C) media forum.SU2C has provided funding for the Epigenetics Dream Team that is collaborating on the scientific evaluation of SGI-110.The randomized Phase 1/2 first-in-human dose escalation study enrolled 66 patients with previously treated intermediate or high-risk myelodysplastic syndromes (MDS) or AML as of March 28, 2012.Of seven evaluable refractory AML patients who had adequate hypomethylation with no prior resistance to hypomethylating agents (HMAs),

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Klnr Mitegen Announces Distribution Agreement with Mexico Diffractia S. de R.L.de C.V.
LAHORE:The construc nb 550 tion of six-kilometre Elevated Expressway from the Ravi River Bridge to Kala Shah Kaku has been approved.Punjab Chief Minister Shehbaz Sharif approved the project in a meeting held at the CM House on Saturday.The road is an intersection for traffic coming from Gujranwala, Sheikhupura and Shahdra Town towards Lahore. The road between Shahdra Morr to Barkat Town is a bottleneck for traffic coming in and out of the city. It is the only entrance into Lahore for traffic coming from Islamabad and Gujranwala via Grand Tru adidas samba schuhe nk Road (GT Road).Shehbaz said six lanes are for general traffic, whereas two lanes are for the metro buses. The elevated expressway would have a 4.5 km long bridge and 1.5 km would be on the ground level, he added.鈥淢odern infrastructure will help grow our country new balance 740 鈥檚 economy and promote industrial and trade activities,鈥?he said, adding that the Punjab government has spent billions of rupees on infrastructure projects. The elevated expressway would address tr Scientists have solved a decade-old mystery that could eventually lead to the development of earlier tre dunk nike high atments for one of the world鈥檚 deadliest diseases, which affects up to 2 billion people.Research carried out by the University of Sussex and the Polish Academy of Sciences has identified two key proteins that allow mycobacterium tuberculosis, the causative agent of tuberculosis (TB), to 鈥渓ay low鈥?within cells designed to destroy them.More than 10.6 million people worldwide fell ill and 1.7 million died from tuberculosis last year while a quarter of the world has latent TB, which will develop into active tuberculosis for one in  dunk nike store ten victims years or even decades later. TB is notoriously difficult to treat with current drug treatments often producing debilitating side effects within patients, including muscle wastage and loss of sight.Previously, the Doherty group at the University of Su yeezy ssex鈥檚 Genome Damage and Stability Centre discovered that mycobacteria repair DNA breaks using an enz

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Iceo New Tools for Precise Large DNA Insertions Developed
  NEW YORK 鈥?Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a pha new balance sneaker se I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30鈥揙ct. 3.Among 11 evaluable patients who  nike dunk high had received more than the lowest dose of the vaccine, six (54 percent) had clinical benefit. One patient with ovarian cancer had a complete response that lasted 89 weeks, one patient with gastroesophageal cancer had a partial response that lasted 16 weeks, and four patients (two with colon cancer, one with prostate cancer, and one with ovarian cancer) had stable disease.鈥淚mmunotherapy marshals the exquisite specificity of the immune system to destroy can dunk homme cer, and some types may have potentially fewer side effects than traditional chemotherapy,鈥?  US entrepreneur Elon Musk said Thursday he'd re adidas samba plataforma ceived tentative approval from the government to build a conceptual "hyperloop" system that would blast passenger pods down vacuum-sealed tubes from New York to Washington at near supersonic speeds."Just received verbal govt approval for The Boring Company to build an un adidas campus 80s derground NY-Phil-Balt-DC Hyperloop. NY-DC in 29 mins," the flamboyant CEO of Tesla and SpaceX tweeted, using abbreviations for New York, Philadelphia, Baltimore and Washington DC.New York and Washington are separat adidas campus blanche ed by some 330 kilometers (200 miles) -- currently, an approximately three-hour journey by train or one hour and 15 minutes flying.High-speed Hyperloop project ready for key test in NevadaThe US Department of Transportation forwarded queries for comment to the White House, which offered a statement that neither confirmed nor outright dismissed the bombastic announcement."We have had promising conversations to date, are committed to transformative infrastructure p

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  The IntelliCap electronic oral drug delivery technology, created by medtech innovator Medimetrics, has won a prestigious European 鈥楬igh-Tech Innovation Award鈥?from Accenture, the global management consultancy.As Medimetrics CEO Olaf Weiner explained: 鈥淲e are delighted to win this award, in recognition of the unique capabilities of the technology behin nike air force d our drug delivery systems nike store dunks . The use of IntelliCap will help deliver a revolution in healthcare which both saves costs and improves the outcomes for patients.鈥漈he IntelliCap system was introduced into the market in 2011. An increasing number of pharma companies are using this powerful tool in the early-stage development and life cycle ma dunk nike high nagement of drugs. This unique, interactive device enables personalization of medications and treatments, empowering scientists to establish quickly the effective medication dose and delivery requirements. This reduces the risk of failure in expensive, late stage clinical trials, due to lack of safety or ef  LAHORE:After gaining mainstream acclaim for her Coke Studio de ugg hausschuhe but, singer Naseebo Lal has belted out a cover of Nusrat Fateh Ali Khan鈥檚 song Gin Gin Taare Langdiyan Raatan.However, this is just the beginning for the Dukhi Dil Mera crooner. Looking at the response to the track, she has decided to put out an entire album, paying tribute to the late qawwali giant.Talking to The Express Tribune, Naseebo said she has chosen different tracks sung by Nusrat at different stages of his career and the videos will be shot in the two cities that were closest to his heart 鈥?Faisalabad and Lahore.鈥淭he album will be released after three months. The idea is to acknowledge the work of Nusrat Fateh Ali Khan and honour his contributi new balance donna on for our country. Although I do not have resources like those of Coke Studio, I am trying to give my cover songs a similar feel,鈥?she said.Interestingl stanley y, the songs are being done at Sargam Studios, the place Nusrat called his second home. According to Naseebo, the recording

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Anaf Hackers mint crypto-currency with technique in global ;ransomware; attack
  Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation. They also unearthed a means by which lactate sends signals to the cells, helping modify and strengthen neuronal functions.Details of their study were reported in theJournal of Biological Chemistryon June 10, 2023.Lactate is a byproduct of exercise and metabolism. Glucose gets converted into lactate when oxygen supplies to cells are limite nbbalance d, giving the  yeezy 350 brain a source of energy. Lactate levels in fetal brains increase from the middle state of gestation, highlighting the significant role it has in brain development and neuronal differentiation.Want more breaking news?Subscribe to Technology Networks鈥?daily newsletter, delivering breaking science news straight to your inbox nike dunk donna  every day.Subscribe for FREE  KARACHIakistan鈥檚 emphatic 3-0 T20I series win over world champions West Indies has greatly impressed pundits, who have heaped special praise on captain Sarfraz Ahmed鈥檚 ability to lead the team in addition to admiring the all-round display by the Men in Green.鈥淪arfraz is a born leader. His domination on the field shows and he has great camaraderie with his players,鈥?said former captain Rashid Latif, who also added that the wicketkeeper has what it takes to lead the team in the other two formats as well.After resounding wins in the first two T20Is in Dubai last weekend, Pakistan completed the series whitewash with  stanley cup another convincing victory 鈥?eight-wicket win 鈥?at Abu Dhabi鈥檚 Zayed Stadium Tuesday night.Sarfraz hails 鈥榯otal te new balance femme am effort鈥橧n all three games, the  adidas campus 00's bowlers stifled the West Indian batsmen while the batting line-up looked in control on pitches that suited the hosts鈥?style of play.And Latif was extremely impressed with the display despite the fragility of the West Indian line-u

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  Spotfire聽and聽BioImagene聽have announced that they have integrated their products to speed decision-making for life science customers. The Spotfire data experi nike dunk ence has bee dunk nike low n integrated with BioImagene's Image Informatics technology to help turn researchers into difference-makers that drive companies' day-to-day competitiveness and success with respect to drug research. The combined offering will be generally available to customers from May onwards. "Our customers have made significant investments in capturing, analyzing, and sharing image data," said Gauri Naik, Marketing Director of BioImagene."However, they have traditionally lacked the tools to combine high content screening data with raw images for better, faster analysis." "Integrating with nike air forces 1  Spotfire analytics gives our customers the premium experience for integrating these data sources and analyzing the results, accelerating the research cycle and creating an advantage in the market." The integration between BioImagene and Spotfire e  LONDON:Buoyed by the return of Harry Kane, Tottenham Hotspur will look to arrest their current slump and improve their dismal record at the Emirates Stadium in Sunday's derby against Arsenal.Though they remain the last unbeaten team in the Premier Le stanley cups ague, Tottenham have gone six games without victory in all compe adidas campus damen titions since their stunning 2-0 defeat of Manchester City a month ago.Wednesday's 1-0 loss to Bayer Leverkusen left them in third place in their Champions League group and manager Mauricio stanley-cup  Pochettino concedes preparation for the 179th North London derby has not been ideal.Ranieri cheered by Leicester resilience"It's true that we are not in a positive situation," said the Argentine, whose side are fifth in the table ahead of the weekend's fixtures, three points below second-place Arsenal. "In the six games after Manchester City we have struggled to win games -- four draws and two defeats. We are very conscious about that. We need to work hard and try more than before."We are in

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Cetk United hit with fresh controversy as passenger ;stung by scorpion;
LONDON:Out of favour Manchester United midfielder Bastian Schweinsteiger has been left out of the club's squad for the Europa League group stage.The 32-year-old has reportedly been forced to train with United's reserves this season as new boss Jose Mourinho looks to sell the German Wo adidas campus rld Cup winner.Transfer window round-up: The summer of spendingSchweinsteiger has yet to make an appearance under Mourinho, who has told the former Bayern Munich star it will be "very difficult" to give him any playi stanley cup ng time this season.Schweinsteiger has been named in United's Premier League squad but he will be ineligible to play in Europe after being excluded from the 27-man list submitted to UEFA.Premier League spending crosses 拢1 billion barrierThe German had stated on the eve of his 121st and samba adidas og  final international appearance for Germany on Tuesday that it was still his "absolute dream" to help United this season.Teenage defenders Timothy Fosu-Mensah and Axel Tuanzebe, who has yet to make his first-team  Artificial intelligence and machine learning are among the latest t yeezy slide ools being used by cancer researchers to aid in detection and treatment of the disease.One of the scientists working in this new frontier  jordans damen of cancer res dunk nike high earch isUniversity of Colorado Cancer CentermemberRyan Layer, PhD, who recentlypublished a studydetailing his research that uses big data to find cancerous mutations in cells.鈥淚dentifying the genetic changes that cause healthy cells to become malignant can help doctors select therapies that specifically target the tumor,鈥?says Layer, an assistant professor of computer science at CU Boulder. 鈥淔or example, about 25% ofbreast cancersare HER2-positive, meaning the cells in this type of tumor have mutations that cause them to produce more of a protein called HER2 that helps them grow. Treatments that specifically target HER2 have dramatically increased survival rates for this type of breast cancer.鈥漇cientists can evaluate cell DNA to identify mutations, Layer says, but the cha

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Khea Genomatix Sequencing Analysis Solution GGA Installed at Barcelona Centre for Genomic Regulation
  Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.  air force 1 damen To do so, they have to pass through the walls of small blood vessels. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Goethe University Frankfurt have now shown that tumour cells kill specific cells in new balance 550  the vascular wall. This enables them to leave the vessels and establish metastases, a process facilitated by a molecule called DR6.The most common cause of cancer deaths is not the primary tumour itself but metastases that subsequently form. Most tumour cells spread via the bloodstream. To do so, individual tumour cells have to enter blood vessels and leave the bloodstream again at remote locations.Together with scientists at the universities of Cologne and Heidelberg, the  yeezy Research Group led by Stefan Offermanns  KARACHI:The Sindh High Court (SHC) asked on Wednesday the petitioner to argue on the maintainability of his petition seeking to restrain former petroleum minister Shahid Khaqan Abbasi from assuming charge of the interim prime minister, following disqualification of his predecessor Mian Nawaz Sharif by the Supreme Court last week.A two-judge bench, headed by Justice Munib A adidas campus damen khtar, also directed the petitioner to submit on August 10 supporting documents on t adidas campus 80s he ineligibility of the respondent.Advocate Muhammad Nadeem Sheikh said that the respondent, Abbasi, who is the former minister for petroleum and natural resources, was named as accused in a National Accountability Burea adidas campus uomo u (NAB) case registered in 2015 regarding award of a liquefied natural gas (LNG) import contract.Interim PM: Abbasi鈥檚 eligibility challenged in SHCOther suspects include former petroleum secretary Abid Saeed, Inter State Gas Systems Managing Director Mobin Saulut, Engro's Chief Executive Officer Emranul Haq and Sui Sout

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Abyl Last chance: Civil judges get three months to prove themselves
  Cyclic molecules are everywhere, and everything around us stems from the way they a nike jordan re assembled: not just taste, colour and smell but also (for example) pharmaceutical drugs. Nature by itself forms molecular rings of different sizes and chains of rings of varying lengths that scientists are able to reproduce artificially. Chemists from the University of Geneva (UNIGE) have now devised a new technique for creating these chains of molecular rings that do not use standard chemical interactions but contact wit yeezy h large molecular surfaces that are electron-poor and do not exist in nature. Unlike with standard procedures, this new technique works by autocatalysis 鈥?the rarest, but also t adidas yeezys he most ambitious, type of transformation that exists in chemistry. The results of this research, published in the journal Angewandte Chemie, open up new prospects for molecular cyclization and also provide the first part of the answer to an old contradiction in classical chemistry.The molecules that surround u  KARACHIakistan Super League (PSL) Chairman Najam Sethi has said the super league final wil new balance blanche l be held in Lahore if cricket fans and citizens of Pakistan are ready to watch the game without foreign players.鈥淭he foreign players have refused to play the final in Lahore after Monday鈥檚 blast but if the citizens of Pakistan want the final of the PSL to be held in Lahore despite foreign players not participating in the final then the final will be held in Lahore,鈥?Sethi said in his statement.He said that security agencies have promised to provide full security for the match and left it to the fans to decide if they want the final in Lahore or not.Lahore blast: what does it mean for the PSL final?Meanwhile, Punjab Law Minister Rana Sanaullah adidas samba  said Punjab was ready to host the PSL final with full security and that Lahore was s stanleycup afe for the players even after Monday鈥檚 incident. Before opening of the league, the Pakistan Cricket Board (PCB) had held a meeting with the foreign players to ensure them

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Nexf Ahmed Faraz s stolen medals not yet found
BEIJING:Following a meeting of the Joint Cooperation Committee (JCC) of the China-Pakistan Economic Corridor (CPEC), Minister for Planning, Development and Reform Ahsan Iqbal on Friday said China and  nb 550 Pakistan new balance homme  were entering a new phase of the agreement under which they would set up nine industrial zones in the country.Out of these, two industrial zones will be set up by the federal government in Islamabad and Karachi, while the rest will be established in Punjab, Sindh, Khyber-Pakhtunkhwa, Balochistan , Gilgit-Baltistan, Fata and Azad Kashmir.Govt anticipates $4b investment in three industrial zones along CPECAdditionally, Iqbal said during the meeting rail-based mass transit projects for  adidas samba adidas all provincial capitals of the country including Lahore, Peshawar, Karachi and Quetta were also approved.These rail projects will be almost similar to the Orange Line Train currently being constructed in Lahore. 鈥淎ll of these four projects have been made part of the CPEC framework.鈥滳PEC was covering th Amgen has announced that it has entered into a definitive agreement with F. Hoffmann-La Roche ("Roche") to acquire Roche's rights to filgrastim and pegfilgrastim in approximately 100 markets, effective Jan. 1, 2014.Roche has held the rights to filgrastim and pegfilgrastim under license from Kirin-Amgen, Inc. (a joint venture between Amgen and Kirin Holdings Co. Limited, of Japan) in Eastern Europe, Latin Amer yeezy ica, Asia, the Middle East and Africa since 1989.The franchise generated approximately $200 million in sales in these territories in 2012.Filgrastim and pegfilgrastim are white blood cell boosting therapeutics used to reduce the risk of infection in patients receiving chemother dunk nike store apy. They are marketed by Amgen in the United States and Europe under  yeezy boost the trade names NEUPOGEN庐 and Neulasta庐, respectively."This agreement will enable Amgen to reach more patients around the world with two of our innovative medicines," said Robert A. Bradway, chairman and chief executive officer of Amgen. "T