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Rbcn ReNeuron Announces Filing IND Application to the FDA for ReN001
  Lancaster Laboratories provides GMP and GLP services, including protein characterization, cell bank testing, viral clearance studies and method validation to its clie nike dunk high nts across the globe.Lancaster Laboratories president Timothy S Oostdyk said their company is seeking to work with BioAzure to enable Indian biotech companies to achieve their regulatory compliance objectives for their product development and manufacturing activiti nike dunk donna es."With the goal of delivering a seamless service experience, we plan to focus on ways to customize our service mo af1 shoes dels to cater specifically to Indian companies," Oostdyk added.  Hackers attending this weekend's Def Con hacking convention in Las Vegas were invited to break into voting machines and voter databases in a bid to uncover vulnerabilities that could be exploited to sway election results.The 25-year-old conference's first "hacker voting village" opened on Friday as part of an effort to raise awareness about the threat of election results being altered through hacking.Hackers crammed into a crowded conference room for the rare opportunity to examine and attempt to hack some 30 pieces of election equipment, much of it purchased over eBay, includin boots kaufen g some voting machines and digital voter registries that are currently in use."We encourage you to do stuff that if you did on election day the adidas samba rose y would probably arrest you," said Johns Hopkins computer scientist Matt Blaze, who organised the segment in a conference room at the Caesar's Palace convention center.CIA thinks Putin directed US election interference: reportThe exercise featured a "cyber rang nb 550 e" simulato

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Kypf Money owed by Sindh: PM rejects call for recovering power bills from tax pool
  Dako, an Agilent Technologies company,  asics gelkayano and ONO PHARMACEUTICAL CO., LTD. today announced a new partnership to develop a potential diagnostic test specifically for use with Opdivo in the treatment of non-small cell lung cancer (NSCLC). This test is being investigated for its diagnostic utility to determine which patients are most likely to respond to Opdivo.Lung cancer is the most common cause of cancer-related mortality worldwide, and is responsible for  nike high dunk more than 1.5 million deaths per year(1). The demand for personalized medicine continues to increase, as it may provide a way to both improve patient care and better manage health care costs by targeting treatment to the individuals most likely to benefit from it."We are pleased to be chosen as ONO's partner for the development of a companion diagnostic test for this promising drug," said Jacob Thaysen, preside jordans damen nt of Agilent's Diagnostics and Genomics Group. "Today's announcement follows several other collaborative agreements in the compa  UNITED NATIONS:The Watchlist on Children and Armed Conflict, a network of organisations advocating for children in war zones, urged the United Nations to add 11 parties to the blacklist of countries, armed groups responsible for violating children鈥檚 rights, said a statement released by the group on Wednesday.The Watchlist, established in 2001, recomme adidas campus femme nded that the Saudi Arabia-led coalition in Yemen and the Tehreek-i-Taliban (TTP) Pakistan be part of the list. Last year, however, the Saudi Arabia-led coalition in Yemen was taken off the list after the country, and its supporters, threatened to withdraw fundin adidas campus wei脽 g for various United Nations (UN adidas campus ) programmes.UN documents nearly 1,500 child soldiers in Yemen"The new secretary-general [Antonio Guterres] has an opportunity to send a clear message to all member states that a party to the conflict is listed for one reason alone 鈥?a pattern of documented, UN verified evidence of grave violations against children," said Watchlist advocacy officer D

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Tvxm Insights Into Lung Tumor Biology and Potential Drug Targets
  Hybrigenics has announced the appointments of Remi Delansorne as Chief Executive Officer, and D nike dunk high aan Ellens as Chairman of the Board. The appointments follow the death earlier this year of Bart Kwist, president and CEO.Remi Delansorne was  adidas yeezy previously vice-president for R&D at Hybrigenics. The appointment of an insider is confirmation that the company plans to pursue the same strategy: it will continue its drug discovery efforts, while growing the revenues from high quality proteomics services for public and private research laboratories.Delansorne, 46, has 20 years experience in drug discovery and development. He joined聽Theramex (Monaco) in 1985, a specialist in reproductive endocrinology and hormone-dependent oncology, where he became head of pre-clinical R&D in 1999. Following the takeover of Theramex by Merck-Lipha, he was called in 2002 to head global re yeezy 350 search on diabetes at聽聽Merck KGaA (Lyon, Chilly-Mazarin and Darmstadt). He joined Hybrigenics in 2004 as vice-president for R&D. Dela  ISLAMABAD:The annual inflation rate remained subdued in December, falling further to 3.7% primarily due to a seasonal reduction in prices of items in the food basket, Pakistan Bureau of Statistics (PBS) reported  ugg boots f眉r damen Monday.The annual inflation rate measured by the Consumer Price Index (CPI) - which captures prices of 481 commodities in urban centres - was registered at 3.7% in December compared to the same month of the previous year, reported the PBS.The main reason behind the fall was reduction in prices of both perishable and non-perishable food items and transport fare. Due to the same reasons, the monthly inflation rate decelerated to negative 0.7% last month over November.It was the second consecutive month that the pace of annual inflation slo adidas campus beige wed after increasing for five straight months.Core inflation - measured by excluding energy and food items, which had started picking momentum also - slightly decelerated to 5.2% last month. It was for the first time in half a year that the  nb 574 rate

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Vbbz Stimulating T Cells To Attack Tumors
  Key aspects of the ageing of human cells can be reversed by new compounds developed at the University of Exeter, according to a new stud adidas yeezys y published in Aging.Researchers asse af1 ssed the effects of a range of mitochondria-targeted H2S donors on splicing factor expression, cell proliferation, apoptosis, DNA replication, DNA damage, telomere length and senescence-related secretory complex (SASP) expression in senescent primary human endothelial cells.They reported that all H2S donors produced up to a 50% drop in senescent cell load assessed at the biochemical and molecular level.In other wo asic gels rds, the number of senescent cells (older cells that have deteriorated and stopped dividing) was reduced by up to 50%.The Exeter team also identified two splicing factors (a component of cells) that play a key role in when and how endothelial cells become senescent. The findings raise the possibility of future treatments not only for blood vessels 鈥?which become stiffer as they age, raising the risk of prob  MANSEHRA:The district administration banned all unlicenced crush machines and decided to take legal action against any nb one who defies these restrictions.Officials privy to the development told The Express Tribune on Wednesday action was taken following public complaints about the operation of unlicenced crush machines in Mansehra, Balakot, Oghi and other new balance pour femme  areas.Mansehra DC Iqbal Hussain held a meeting with assistant commissioners and the police to identify all the illegal units in the district and ensure not a single one was left operational.The DC asked the tehsil administration to take action against the owners without taking into account political affiliations or social influence.According to officials, there were dozens of small crushers installed on the banks  new balance 327 of small streams and rivers by owners who never obtained approval from the minerals department and district administration.Published in The Express Tribune, June 2nd, 2016.

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Scpy Hillary or Trump: Hopes and concerns hover over political fraternity
  DNA mutations are es tenis yeezys sential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets. But this proces new balance 480 s can go awry in people with a mutation in a gene called SETD2, leading to a type of aggressive blood cancer, according to a study by Weill Cornell Medicine investigators.Thestudy, published April 20 inCan yeezy boost 350 cer Discovery, found that having a mutation in one of the two copies of SETD2 in B cells can lead to a proliferation of cells that don鈥檛 readily repair their mutated DNA, causing an aggressive type of cancer called diffuse large B cell lymphoma (DLBCL).鈥淗owever, when both copies of this gene are mutated in the cancer cell, it is fatal to the cell, suggesting that drugs that target SETD2 might offer an effective treatment option for this type of lymphoma,鈥?said senior authorDr. Ari Melnick, the Gebroe Family Professor of Hematology/Oncology in the Division of Hematology and Clinical Oncology   ISLAMABAD:The Islamabad High Court (IHC) on Thursday granted a fortnight鈥檚 time to the federal and Khyber-Pakhtunkhwa governments to submit a reply in a case where the appointment of K-P police chief is challenged.Justice Aamer new balance hombre  Farooq granted the time after Additional Attorney General Afnan Karim Kundi and Assistant Advocate General Malik Akhtar Hussain Awan appeared before the cou new balance nere rt and sought time to submit a reply from their respective governments.K-P Additional Inspector General of Police Syed Akhter Ali Shah, who temporarily held the charge of acting IG after the retirement of Nasir Durrani, challenged the appointment of K-P IG Salahuddin Khan Mehsud.New K-P police chief faces court  stanley cups challengePreviously, the court issued notices to the Establishment Division secretary and the newly-appointed K-P police chief over the latter鈥檚 appointment because it is said to be in violation of the apex court鈥檚 judgment regarding unlawful promotions.The petitioner, through his counsel Barrister Mas

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Sxdf Farmers borrow at  much higher rates than industrialists
  New research on how cannabis use alters eating behavior could lead to treatments for appetite loss in chronic illness, according to experts at Washington State University. Using a new procedure to dose lab rats with cannabis vapor, the researchers found how the drug trigger dunk low s hunger hormones. They also identified specific brain regions that shift to 鈥榟ungry鈥?mode while under the influence, according to a report they shared at the Society for the Study of Ingestive Behavior, an international me yeezy 700 eting of scientific experts on eating.鈥淲e all know cannabis use affects appetite, but until recently we鈥檝e actually understood very little about how or why,鈥?explained Jon Davis, Ph.D., researcher in the Department of Integrative Physiology and Neurosciences at Washington State. 鈥淏y studying exposure to cannabis plant matt nike airforce er, the most widely consumed form, we鈥檙e finding genetic and physiological events in the body that allow cannabis to turn eating behavior on or off.鈥滱 recent wave of cannabis lega  MULTAN:At least two women and a child suffered burn injuries after unknowingly using water laced with acid at a聽wedding聽in Vehari, police said.A wedding was taking place at Nawab Marki Marriage club聽in聽People's Colony where a woman used the acidic water to wash up her toddler. The child started screaming when the water touched his skin, burning his genitals, while the woman burnt her hand trying to get it off him.Another woman received similar injuries when she poured the  ugg boots damen water on herself. All three victims were shifted to聽Nishtar Hospital, Multan.Act of vengeance: T stanley cup hree members of a family suffer acid attackDanewal聽police said that the manager of the club fled following the incident and that 聽an invest adidas campus nere igation into the incident has been started.Meanwhile, residents of the area claimed that the mixing of acid with water was a deliberate聽act as some members of the groom's family weren't happy with the marriage. The incident subsequently led to the聽postponement of the ceremony.However, gr

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Ecme Quake kills 272 along devastated Ecuador coast
  Solvay and INEOS have announced that they have signed a Letter of Intent (LOI) to combine their European chlorvinyls activities in a proposed 50-50 joint venture.T dunk he combination would form a polyvinyl chloride (PVC) producer ranking among the top three worldwide. It would build on the strengths of both our companies鈥?industrial assets, the skills of our teams and the complementarity of our geographical presence in order to enhance competitiveness.The joint venture w claquette yeezy ould have pro-forma net sales of EUR 4.3 billion and REBITDA of EUR 257 million, based on 2012 figures.The combined business would have around 5,650 employees in 9 countries and would pool each company鈥檚 assets across the entire chlorvinyls chain.This includes PVC, which is the third most-used plastic in the world, caustic soda and chlorine derivatives. RusVinyl, Solvay鈥檚 Russian joint venture in chlorvinyls with Sibur, is excluded from the tr new balance 990 ansaction.鈥淭his proposed partnership is an ambitious and value-creating industrial   NEW DELHI:Cash machines ran dry and stocks tumbled in India Wednesday after Prime Minister Narendra Modi ordered the withdrawal of 500 and 1,000 rupee notes from circulation in a dramatic blitz on tax evasion.In a televised address to the nation late Tuesday, the Indian premier announced the notes would no longer be legal t adidas velosamba ender from midnight in order " newbalance 574 to break the grip of corruption and black money".The government plans to print new 500 and 2,000 rupee notes, which will be rolled out later in the week.All banks and cash machines were ordered to close on Wednesday in preparation for the turnaround, triggering a late night rush by customers to withdraw smaller notes from ATMs.Customers will be able to exchange their old bills for new notes or deposit them into their accounts but face th stanley shop e prospect of major scrutiny by tax authorities if they cannot account for a sudden swell in their balance.India withdraws 500 and 1,000 rupee notes in fight against graft, 'black money'While the move was

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Ddti Quaid-e-Azam Apparel Park will help boost economy
  A new understanding as to how plants defend themselves against some pathogens that cause crop diseases is proposed by researchers from the University of Hertfordshire to help scientists breed new, more successful jordan2  disease-resistant agricultural crops. The new concept is called effector-triggered defence or ETD.Breeding agricultural crops for resistance against disease pathogens is essential in the quest to secure global food production. However, despite efforts to control them, crop diseases still account for fifteen percent of the losses in the world's food production. Farmers spray their crops with fun nike sb dunk gicides to control these plant diseases, but their effectiveness is limited as disease pathogens mut nike dunk sb ate to become insensitive to the fungicides.By exploiting new molecular and genetic insights, the BBSRC-funded research, done in collaboration with Pierre de Wit from Wageningen Agricultural University in the Netherlands, provides a better understanding of the defence system of crop plants  Rumours of Ranveer Singh and Ranbir Kapoor's 'cold war' have been abuzz since Deepika renewed her friends uggs hip with her ex, Ranbir. The two stars however, have rubbished such rumours by dancing聽together to each other's songs at a party hosted by Karan Johar on Satu adidas samba vegan rday.Ranveer perfectly shuts down reporter asking Deepika about engagement rumoursRanveer danced to t uggs hausschuhe he Tamasha star's hit number, Dilliwali Girlfriend.聽https://www.instagram.com/p/BIO2M56Abem/?taken-by=deep.veer.fcThe two took the stage to replicate the聽Badtameez Dil dance moves.聽Badtameez Dil with Ranbir Kapoor and Ranveer Singh! pic.twitter.com/1ar1A94iQo鈥?RanbirKapoor.Net (@RanbirKapoorFC) July 23, 2016Together they set the dance floor ablaze by rocking to Jumma Chumma Dey Dey.聽https://www.instagram.com/p/BIO19Ucg_pR/?taken-by=deep.veer.fcBollywood A-listers like Shah Rukh Khan, Deepika Padukone, Anushka Sharma, Sonam Kapoor, Alia Bhatt and many others, attended the party.Did Ranbir Kapoor just choose Fawad Khan over Katrin

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Qhzn Heartbreak city: Bloodied Peshawar turns into battleground of blame
  Applied Biosystems Group, an聽Applera Corporation business, has announced that it has completed its previously announced equity investment in privately held VisiGen Biotechnologies.Concurrent with its investment, Applied Biosystems also entere dunks nike low d into a scientific collaboration agreement with VisiGen. The VisiGen investment is part of Applied Biosystems鈥?strategy of maintaining its position in DNA sequencing by complementing its internal investments in new and existing sequencing technologies with promising ne yeezy xt-generation appro nike af1 aches.VisiGen鈥檚 technological approach to DNA sequencing is based on the ability to analyze a single molecule of DNA in real-time.  FAISALABAD:The City District Government has designated 26 points for collection of hides in the city during Eid days.A spokesman for the local administration said on Wednesday that in Lyallpur Town, the hide collection points have been fixed at Eidgah Road outside Aminpur Bazaar, adidas samba homme  near Darbar Baba Qaim Sain outside Graveyard, Riaz Shahid Chowk near WASA Office, Chandni Chowk near MC Boys High School Islam Nagar, whereas hide collection points in Iqbal Town are at WASA Warehouse near Novelty Bridge, Mumtaz Garden Gulshan-e-Rafiq nb balance  Rodex Road, Stop No 5 Hilal Road 224-RB Wazir Khan Wali and Overhead Water Tank Chowk Mandi Quarter.鈥楢nimal hides worth Rs7b wasted annually鈥橧n Madina Town, the hide collection points have been established at Nishatabad in front of Chenab Fabrics and Saeed Colony No 1 near Grav adidas sambarose eyard Madina Town whereas these points in Jinnah Town will be at MI Middle School near Lal Dispensary Gulberg, outside MC Boys High School Ghulam Muhammad Abad outside Union Council No 280

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Keqq Chahal;s three restricts Zimbabwe to 126 in second ODI
  A new study shows how errors in a specific gene can cause grow adidas yeezy th defects associated with a rare type of dwarfism.During the study, published today in Nature Genetics, an international team of scientists led by the University of Birmingham looked at genetic information from more than 250 people around the world with microcephalic dwarfism, a group  jordans damen of disorders charac dunk high terised by short stature and reduced head size.They found that 29 of the individuals had faulty versions of a gene called DONSON.Tests on cells growing in the laboratory revealed that this gene plays a crucial role in ensuring DNA is copied correctly when cells divide and grow. Cells from patients with mutations in the DONSON gene had difficulty in efficiently replicating their DNA and protecting it from uncontrolled damage, ultimately leading to the growth defects typical of microcephalic dwarfism.This research raises the potential of more accurate diagnoses for patients with genetic microcephaly, in addition to providing a  ISLAMABAD:The government and opposition parties are likely to evolve consensus on two pro-women bills and plan to present them in parliament after the budget debate.Progress on the two important bills on violence against women and honour killings has been stalled since the joint parliamentary session in April after Jamiat Ulema-e-Islam-Fazl objected to some provisions in both of these bills.No safe passage f adidas campus 00's or pro-women  nb 550 bills in G-BAn agreement between the government and opposition was re nb ached in a meeting held last week, sources told The Express Tribune.The JUI-F had opposed the anti-honour killings bill, saying the law should not be specific for women alone but should also include children, transgender, etc. The government succumbed to the JUI-F鈥檚 pressure and there was no headway till June 3.The Cabinet Committee on Law Reforms, which includes Law Minister Zahid Hamid, PM鈥檚 Special Assistant on Law and Justice Barrister Zafarullah Khan, met JUI-F lawmaker Naeema Kishwar along with o