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Fzne Genome Wide Study of Transcription in Yeast Redefines the Concept of Promoters
  The IntelliCap electronic oral drug delivery technology, created by medtech innovator Medimetrics, has won a prestigious European 鈥楬igh-Tech Innovation Award鈥?from Accenture, the global management consultancy.As Medimetrics CEO Olaf Weiner explained: 鈥淲e are delighted to win this award, in recognition of the unique capabilities of the technology behin nike air force d our drug delivery systems nike store dunks . The use of IntelliCap will help deliver a revolution in healthcare which both saves costs and improves the outcomes for patients.鈥漈he IntelliCap system was introduced into the market in 2011. An increasing number of pharma companies are using this powerful tool in the early-stage development and life cycle ma dunk nike high nagement of drugs. This unique, interactive device enables personalization of medications and treatments, empowering scientists to establish quickly the effective medication dose and delivery requirements. This reduces the risk of failure in expensive, late stage clinical trials, due to lack of safety or ef  LAHORE:After gaining mainstream acclaim for her Coke Studio de ugg hausschuhe but, singer Naseebo Lal has belted out a cover of Nusrat Fateh Ali Khan鈥檚 song Gin Gin Taare Langdiyan Raatan.However, this is just the beginning for the Dukhi Dil Mera crooner. Looking at the response to the track, she has decided to put out an entire album, paying tribute to the late qawwali giant.Talking to The Express Tribune, Naseebo said she has chosen different tracks sung by Nusrat at different stages of his career and the videos will be shot in the two cities that were closest to his heart 鈥?Faisalabad and Lahore.鈥淭he album will be released after three months. The idea is to acknowledge the work of Nusrat Fateh Ali Khan and honour his contributi new balance donna on for our country. Although I do not have resources like those of Coke Studio, I am trying to give my cover songs a similar feel,鈥?she said.Interestingl stanley y, the songs are being done at Sargam Studios, the place Nusrat called his second home. According to Naseebo, the recording

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Ycts SC says page representing it on Facebook is fake
  Spotfire聽and聽BioImagene聽have announced that they have integrated their products to speed decision-making for life science customers. The Spotfire data experi nike dunk ence has bee dunk nike low n integrated with BioImagene's Image Informatics technology to help turn researchers into difference-makers that drive companies' day-to-day competitiveness and success with respect to drug research. The combined offering will be generally available to customers from May onwards. "Our customers have made significant investments in capturing, analyzing, and sharing image data," said Gauri Naik, Marketing Director of BioImagene."However, they have traditionally lacked the tools to combine high content screening data with raw images for better, faster analysis." "Integrating with nike air forces 1  Spotfire analytics gives our customers the premium experience for integrating these data sources and analyzing the results, accelerating the research cycle and creating an advantage in the market." The integration between BioImagene and Spotfire e  LONDON:Buoyed by the return of Harry Kane, Tottenham Hotspur will look to arrest their current slump and improve their dismal record at the Emirates Stadium in Sunday's derby against Arsenal.Though they remain the last unbeaten team in the Premier Le stanley cups ague, Tottenham have gone six games without victory in all compe adidas campus damen titions since their stunning 2-0 defeat of Manchester City a month ago.Wednesday's 1-0 loss to Bayer Leverkusen left them in third place in their Champions League group and manager Mauricio stanley-cup  Pochettino concedes preparation for the 179th North London derby has not been ideal.Ranieri cheered by Leicester resilience"It's true that we are not in a positive situation," said the Argentine, whose side are fifth in the table ahead of the weekend's fixtures, three points below second-place Arsenal. "In the six games after Manchester City we have struggled to win games -- four draws and two defeats. We are very conscious about that. We need to work hard and try more than before."We are in

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Abyl Last chance: Civil judges get three months to prove themselves
  Cyclic molecules are everywhere, and everything around us stems from the way they a nike jordan re assembled: not just taste, colour and smell but also (for example) pharmaceutical drugs. Nature by itself forms molecular rings of different sizes and chains of rings of varying lengths that scientists are able to reproduce artificially. Chemists from the University of Geneva (UNIGE) have now devised a new technique for creating these chains of molecular rings that do not use standard chemical interactions but contact wit yeezy h large molecular surfaces that are electron-poor and do not exist in nature. Unlike with standard procedures, this new technique works by autocatalysis 鈥?the rarest, but also t adidas yeezys he most ambitious, type of transformation that exists in chemistry. The results of this research, published in the journal Angewandte Chemie, open up new prospects for molecular cyclization and also provide the first part of the answer to an old contradiction in classical chemistry.The molecules that surround u  KARACHIakistan Super League (PSL) Chairman Najam Sethi has said the super league final wil new balance blanche l be held in Lahore if cricket fans and citizens of Pakistan are ready to watch the game without foreign players.鈥淭he foreign players have refused to play the final in Lahore after Monday鈥檚 blast but if the citizens of Pakistan want the final of the PSL to be held in Lahore despite foreign players not participating in the final then the final will be held in Lahore,鈥?Sethi said in his statement.He said that security agencies have promised to provide full security for the match and left it to the fans to decide if they want the final in Lahore or not.Lahore blast: what does it mean for the PSL final?Meanwhile, Punjab Law Minister Rana Sanaullah adidas samba  said Punjab was ready to host the PSL final with full security and that Lahore was s stanleycup afe for the players even after Monday鈥檚 incident. Before opening of the league, the Pakistan Cricket Board (PCB) had held a meeting with the foreign players to ensure them

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Uiko Shrimp and Lobster Dishes May Come With Elevated PFAS Risk
  New research by Yale University scientists reports the discovery of 鈥渉yperhotspots鈥?in the human dunk low  genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average.Exposure to UV radiation is the major cause of skin can yeezy 500 cer. Screening the hyperhotspots could offer a new means of predicting a person鈥檚 skin cancer risk.The study was published in the November edition of Proceedings of the National Academy of Sciences (PDF).Sc dunk low mujer ientists knew of hotspots, but not of ultra-sensitive hotspots.鈥淭hese are 100 times more sensitive than other sites in the genome,鈥?saidDouglas Brash, senior research scientist in therapeutic radiology and dermatology and a member of the Yale Cancer Center. He led the research.Named 鈥渃yclobutane pyrimidine dimer (CPD) hyperhotspots鈥?after the type of DNA damage caused by ultraviolet light, hyperhotspots can be thought of as 鈥渂ullseyes鈥?that attract damaging radiation. In the study, they occurred most oft  ISLAMABAD:Afghan Ambassador to Pakistan Dr Omar Zakhilwal met on Friday Jamiat Ulema Islam-Fazl chief Maulana Fazlur Rehman, and sought his help in reducing tension between Afghanistan and P nb 9060 akistan.An important, deep and detailed discussion with JUI leader Mawlana Fazal Rahman on general and current situation! pic.twitter.com/wSfvFnq1aH— Dr Omar Zakhilwal (@DrOmarZakhilwal) March 10, 2017The meeting came at a time  adidas campus damen when relationship between the uneasy neighbours is tense, as Pakistan accused Afghanistan of harbouring terrorists who allegedly carried out the February terror attacks in the country, which claimed over 100 lives.While the military handed over a list of 76 militants to Afghan embassy officials, demanding action against them; au adidas campus beige thorities also closed the Pak-Afghan border, and shelled hideouts of militants belonging to the banned Jammatul Ahrar 鈥?a breakaway faction of the Tehreek-e-Taliban Pakistan."I had substantive and detailed discussion with Maulana Fazl Rahman on a

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Ebnw Militant group Ansar Dine threatens France, UN in new video
  Geologists have long known that around 155 million years ago, a 5000 km long piece of continent broke off western Australia and drifted away. They can see that by the 鈥榲oid鈥?it left behind: a basin hidden deep below the ocean known  yeezys 350 as the Argo Abyssal Plain. The underwater feature also lends its name to the newly formed continent: Argoland. The structure of the seafloor shows that this continent must have drifted off to the northwest, and must have ended up where the islands of Southeast Asia are located today. But surprisingly, there is no large continent hidden beneath those islands, only the remnants of small continental fragments that are also surrounde dunk nike store d by much older oceanic basins. So what happened to Argoland? Geologists at Utrecht University have now managed to reconstruct the history of the lost continent. As it turns out, Argol dunk high and is in fragments, but is still there. 鈥淥therwise, we would have been faced with a major scientific problem.鈥? The first Muslim mayor of London admits聽that Ramazan will be tough for  adidas sambarose him this year round."Anyone who knows me knows that I鈥檓 miserable during Ramazan.聽What I usually miss the most is caffeine; I go to lots and lots of boring meetings聽and I need caffeine to keep going," Sadiq Khan said. "This year, in preparation [for Ramazan], I tried to cut down on coffee in the lead up to it. Food isn鈥檛 the issue 鈥?you get over  adidas samba vegan that."While on the subject, he also discussed the general impression of Muslims --and Islam -- around the world and how he intended to cultivate and bring together the Muslim and non-Muslim communities during聽the holy month.London Mayor Sadiq Khan wants to 'educate' Trump on Islam鈥淚f you鈥檙e someone who doesn鈥檛 have Muslim frien adidas adidas samba ds and your only experience of Islam is what you see on the news 鈥?the angry man with a beard doing or saying something terrible 鈥?then you may inadvertently associate that with Islam and think that is what it鈥檚 all about,鈥?says Khan.Speaking about the

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Xsnz Iran says will never use its weapons against anyone, except in self-defense
  Researchers at the Francis Crick Institute have characterised the structure of the SARS-CoV-2 spike protein as well as its most similar relative in a bat coronavirus. The structures provide clues about how the spike evolved and could help inform vaccine design. A characterising feature of SARS-CoV-2, the virus that asic gels  causes COVID-19, is the protein spikes which cover the surface, which th dunk femme e tenis yeezys  virus uses to bind with and enter human cells.  KARACHI:In campus adidas femme  the 1998 Test series in South Africa, Pakistan were in sight of a series win in what was their maiden full tour there. With a 1-0 lead in the bag, the team was closing on a landmark achievement in the final Test at Port Elizabeth. After an engrossing opening day, the second day was washed out.Only three days were left and South Africa had to first finish  adidas samba their innings then had the task of dismissing Pakistan twice inside three days to win the Test and square the series 鈥?anything less would have ensured a series win for the tourists.The  boots kaufen winning moment #ENGvPAK https://t.co/uoL1xGgxHh— England Cricket (@englandcricket) July 26, 2016Five reasons Pakistan lost to England at Old TraffordDismissing Pakistan twice inside three days was, on paper, a momentous task considering the resilience the batsmen had shown in the preceding Johannesburg and Durban Tests.But in the end it turned out to be one of the easiest coup de grace ever administered in Test history. Forget about pla

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Wxqc Selvita Extends Collaboration with Chiesi Farmaceutici
  Like pirates on a treasure hunt, St. Jude Children's Research Hospital scientists have created the first 3D map of a mouse genome and used it to discover scientific gold. The gold includes insight from machine learning into genomic organization and function during development. The research appears today in the journal Neuron."Understanding the way cells organize their genomes during development will help us to understand their ability to respond to stress, injury and disease," said Michael Dyer, Ph.D., chair of the St. Jude Depar nike store dunk tment of Developmental Neurobiology and Howard Hughes Medical Institute investigator. He and Xiang Chen, Ph.D., assistant member of the St. Jude Department of Computational Biology, are the corresponding authors.The research focused on light-sensing rod cells in the mouse retina. More than 8,000 genes nike store dunk  are tur yeezy 700 ned on or off during retinal development. Thousands of regulatory regions across the genome also play a role. Researchers used technology called ultra-deep  A 45-minute speech by聽Mukesh Ambani, the chairman聽of Reliance Industries 鈥斅燼n Indian conglomerate holding company, announcing free voice services to its users cost the country鈥檚 three existing operators an estimated INR131.66 billion on Thursda adidas campus blu y.Shares of active telecom operators Bharti Airtel, Idea Cellular and Reliance Communications nosedived up to nine per cent as Ambani鈥檚 Reliance Jio priced data tariff for its services at as low as聽INR50/GB, kicking off a tariff war in the country, The Economic Times reported.Shares of Bharti Airtel dropped 6.37 per cent to settle at INR310.70 on Bombay Stock Exchange. Idea Cellular plunged 10.48 per cent to INR83.70, while Reliance Communication slid 8.81 per cent to INR49.15.India intervening in Pakistan's telecommunication signals: PTA鈥淎ll voice calls for Jio customer new balance 991 s will be absolutely free,鈥?the chairman聽revealed in his speech, adding the roaming charges will be zero. In addition to this the company will also offer data at INR50 per GB  adidas campus grau (bas

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Xekh Better Understanding Cancer by Mapping Normal Breast Development
  Critical Outcome Technologies Inc. has announced that it compl nike air forces eted the first tranche of a non-brokered private placement and issued 8,152,500 units at a price of $0.16 per Unit for gross proceeds of $1,304,400. The second tranche of the priva yeezy boost te placement is expected to close by the end of March 2011.Each Unit consists of one common share and one warrant of the Corporation. Each warrant is exercisable into one common shar yeezys e of the Corporation at an exercise price of $0.30 per share for a period of 18 months from the date of issue.The Corporation paid finders' fees to arm's length third parties in connection with this tranche of the private placement in the aggregate amount of $61,680 in cash and issued an aggregate of 385,500 compensation warrants. Each compensation warrant is exercisable into one common share of the Corporation for a period of 18 months from the date of issue at an exercise price of $0.30 per share.The securities issued by the Corporation under the private placement are  KHAR:One student was killed and three others were injured when a bomb was remotely detonated near their vehicle in the Arang tehsil of Bajaur Agency, political administration officials said on Friday.The attack took place in Tauhida adidas samba bad area, where officials of the political administrat boots kaufen ion and security forces conducted a search operation. At least 12 suspects were taken into  adidas campus grise custody for interrogation, official sources said.With Afghan refugees leaving, is Pakistan waving goodbye to carpet-weaving?They added that the vehicle belonged to a government contractor, Nasir, who has already survived two attacks in the past.A levies official was also killed in a similar attack in January in the Mamond area of the same agency. The official, identified as Dilawar Khan, died in the blast at the sentry post at Loy Mohmand near the Pakistan-Afghanistan border.The bomb, planted along the post, was detonated at noon on January 2 using a remote-controlled device.Published in The Express Tribune, Februar

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Oxxk Campus death: Case sought against university management
  Clarifying the mechanism of this harmful pathway is important because nearly 5 million people in the United States suffer heart failure as an age-related disease following heart attacks. Half of them die within five years, and the annual cost for health care, medications and missed work is $32 bill new balance 480 ion.Knowledge of the dysfunctional lipid signaling that triggers heart inflammation and heart failure could be essential to discovering therapeutic treatments for  dunk nike low the millions of aging patients at risk of heart failure after heart attacks.The problem of heart failure is a nonresolving, overactive inflammation at the heart. After a tissue injury, such as death of muscle tissue in a heart attack, the body has a beneficial, early acute inflammation response that removes dead cells and begins repairs to the injur yeezys ed area. In healthy healing, the acute inflammation resolves, and a healing process follows.In healthy healing, particular lipids that the body produces from essential dietary fat appear   KARACHI:The prime minister has failed to fulfil his constitutional responsibility to convene the meeting of the Council of Common Interest [CCI], said Chief Minist adidas campus 00s er Murad Ali Shah at a press conference on Wednesday."If you [PM] cannot fulfil your constitutional responsibilities, then hand over your position to someone else," he demanded. The press conference held at CM House was also attended by Pakistan Peoples Party [PPP] Sindh President Nisar Khuhro. Syed Zafar Ali Shah and other influential people of Dadu district announced their defection to the PPP during the press conference.The CM said he stanley-cup  had made the necessary preparations to present Sindh's case regarding gas, electricity and water ugg hausschuhe  during the CCI meeting that was scheduled on April 28. However, the prime minister postponed the meeting. "This is a sheer disappointment for the people of Sindh," he said, adding that the Constitution states that the province that produces gas has the first and foremost right to use it but the fe

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Whcc Currency: Rupee stable against dollar
  Geochemical calculations by researchers at Tokyo Institute of Technology to determine how the water content of Mars has changed over the past 4.5 billio nike af1 n years suggest as yet unidentified reservo af1 shoes irs of water on the planet.A warmer more watery primordial Martian landscape more closely resembling Earth has long been suggested fro nike dunk m geochemical and geological observations. However, as Hiroyuki Kurakawa and colleagues in Japan point out in their recent report 鈥渢he timing, processes, and the amount of the water loss have been poorly constrained.鈥漈heir latest studies using geochemical meteorite data to understand how the volume of water has changed on Mars over its history suggest there is more water present there now than has so far been observed.Today Martian water is considered to exist chiefly as ice at the poles of the planet. However geological observations of rocks containing water laid sediments suggest that lakes and oceans once existed. Previous studies have focused on the volumes o  LAHORE:The Auditor General of Pakistan (AGP) has criticised the public-private partnership model adopted by Pakistan Railways in a special audit report 2015-16, saying the manner in which the state-owned entity conducted its transactions was questionable and inefficient.The report not only criticised the process of commercial management of loss-making trains, but also highlighted loopholes in awarding the contract of Pakistan鈥檚 first luxury train, Business Express, to a private party.The report said that  boots kaufen the management totally ignored the government policy and no guidance was attained from Infrastructure Project Development Facility (IPDF). It further said that the process of handing over adidas campus damen  Business Express, Hazara Express, Sha adidas samba limar Express and Night Coach was neither planned nor monitored appropriately. In addition, no feasibility study was conducted before awarding the contracts.Pakistan Railways suffers another loss-making year鈥淭he bidding process was not transparent and a lot of irre